Phenotypic and functional analysis of the modification of murine bone marrow dendritic cells (BMDCs) induced by neutral Ginseng polysaccharides (NGP)

Mulberry leaf polysaccharides modulate murine bone-marrow-derived dendritic cell maturation

“…The results from these studies indicated that the polysaccharides could modulate the number of phagosomes and phagocytosis of DC, ACP activity of DC, expression of key surface co-signals molecules on DC and cytokines production by DC. [22][23][24] Our current results confirmed MLPs' role as an immune enhancer by inducing BMDC maturation in that BMDCs, induced by MLPs, showed typical maturation both phenotypically and functionally. These impact on BMDCs by MLP will help vaccines with intensification of special immunity initiation and generation of cellular responses.…”

Ameliorating Effects of Bone Marrow Transplantation and Zinc Supplementation on Physiological and Immunological Changes in γ-Irradiated Rats.

“…BMT post irradiation showed significant elevation of RBC, lymphocytes and BM viable cells which might be attributed to the accelerated restoration of remaining functional hematopoietic cells that is believed to be the major factor in the survival of irradiated mice (Berdan et al, 2011 andMeng et al, 2013). Survival after irradiation actually results from the recovery of several target systems, such as the bone marrow, gastrointestinal tract, skin and hemostatic systems (Widel et al, 2003).…”

A review of the immunomodulatory activities of polysaccharides isolated from Panax species

“… PG WGFPN flower 1.1 × 10 4 neutral Gal: Ara: Glc: Man = 78:14.3:5.2:2.5 (1→4)-β-D-galactan and (1→6)-β-D-galactan. [ 16 ] WGPN root neutral Glc: Gal: Ara = 95.3:3.3:1.3 Starch-like glucans [ 53 ] FGWP root 6.4 × 10 5 Gal: Ara: Glc: Rha: GalA = 9.2:10.1:60.6:1.8:17.8 significantly higher protein content [ 54 ] FGEF-C root Gal: Ara: Glc: Rha: GalA = 10.4:10.5:62.2:2.1:14.3 relatively high amounts of glucose FGEF-A root Gal: Ara: Glc: Rha: GalA = 12.6:10.9:50.9:1.8:23.1 significantly higher ratios of arabinose, galactose, and galacturonic acid, and lower ratios of glucose FGEF-CA root 6.4 × 10 5 Gal: Ara: Glc: Rha: GalA = 16.5:11.4:45.8:3.2:22.3 contained high amounts of rhamnose, arabinose, galactose, and galacturonic acid, with low amounts of glucose RGP1 root neutral Ara:Glc:Gal = 0.02:0.88:0.1 backbones composed of glucose [ 61 ] RGP2-1 root 2.16 × 10 4 neutral Rha:Ara:Glc:Gal = 0.02:0.1:0.77:0.11 backbones composed of glucose NGP root 5.04 × 10 5 neutral Glu O-α-(1→6)-D-Glucan [ 44 ] GPNE-I root 8.03 × 10 4 neutral Glc = 1 a heteropolysaccharide consisting mainly of a glucan domain and type I and II arabinogalactans (AG-I and AG-II) [ 20 ] GPNE-II root 3.15 × 10 4 …”