Phenotypic and Genotypic Characterization of Multidrug-Resistant Enterobacter hormaechei Carrying qnrS Gene Isolated from Chicken Feed in China

Abstract

Enterobacter hormaechei is an opportunistic pathogen. It can cause infections in humans and animals.

Identification and Genetic Characterization of Conjugative Plasmids Encoding Coresistance to Ciprofloxacin and Cephalosporin in Foodborne Vibrio spp.

“…In addition, plasmid-mediated quinolone resistance (PMQR) determinants, which encode a range of resistance-conferring proteins, including the Qnr proteins, the aminoglycoside acetyltransferase AAC(6′)-Ib-cr, and the efflux pumps QepA and OqxAB, have been reported to confer low-level resistance to fluoroquinolones ( 7 , 8 ). Unlike the target site mutations, which can be passed onto future generations, the plasmid-borne PMQR genes can not only enhance the ability of bacteria to survive against the antimicrobial effects of antibiotics but also accelerate the dissemination of resistance genes among a diverse range of bacterial species through horizontal transfer of the resistance-encoding plasmids ( 9 , 10 ).…”