Phenotypic drug discovery: a case for thymosin alpha-1
Enrico Garaci,
Maurizio Paci,
Claudia Matteucci
et al.
Abstract:Phenotypic drug discovery (PDD) involves screening compounds for their effects on cells, tissues, or whole organisms without necessarily understanding the underlying molecular targets. PDD differs from target-based strategies as it does not require knowledge of a specific drug target or its role in the disease. This approach can lead to the discovery of drugs with unexpected therapeutic effects or applications and allows for the identification of drugs based on their functional effects, rather than through a p… Show more
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