Phenotypic variability in unweaned 3-week-old Zucker rats

Effects of age and diet on plasma lipid and glucose concentrations in genetically lean or fat chickens

“…This latter observation is in good agreement with those of Whitehead and Griffin (1982) who showed that the selection of broilers for fatness and leaness on the basis of high and low plasma triglyceride concentrations was more efficient when the birds were fed on a low-fat diet. A higher (although not significant) level of plasma phospholipids was found in the fat birds, implying a higher HDL concentration, as observed in some other obesities (Zucker and Zucker, 1962 ;Bach et al, 1981 (Fiser et al, 1974 ;Palmer et al, 1978 ;Boulange et al, 1981), triglyceridemia increased markedly and as a linear function of the injected detergent dose. We did not observe a plateau in the response.…”

“…One characteristic of most mammalian obesities is an elevation of plasma lipid concentrations (Zucker and Zucker, 1962 ;York, 1975 (Fruchart et al, 1974) Most mammalian obesities are associated with hyperglycemia, hypertriglyceridemia and hypercholesterolemia (Mayer and Jones, 1953 ;Zucker and Zucker, 1962 ;York, 1975 ;Kaplan and Leveille, 1976 ;Mahler et al, 1976 ;Bach et al, 1981). Higher lipoproteinlipase activity is also very frequently associated with these obesities (Gruen et al, 1978 ;Hartman, 1981 ;McNamara and Martin, 1982).…”