Phenylbutazone-induced pericarditis.

Abstract

EBRiJO 795Increasing disability of a rising diastolic blood-pressure and blurring of the vision due to severe retinopathy were the salient features requiring urgent relief.This was accomplished successfully by resection and an aortic homograft replacement.On the basis of the operative findings and of histological examination of the thrombotic aortic sections the aetiology of the lesion was considered to be consistent with vasculitis.I wish to acknowledge the help of my colleagues, Dr.

Acute non-specific pericarditis.

“…Furthermore, an identical clinical picture of acute non-specific pericarditis can be seen following other infections such as Reiter's disease (Csonka & Oates, 1957), infectious mononucleosis (Gardner, 1959) and lymphogranuloma venereum (Sheldon et al, 1948). Likewise in pericarditis following heart operations (Engle & Ito, 1961); following myocardial infarction (Dressler, 1959a); gunshot wounds to the heart (Wood, 1956); following traumatic haemopericardium (Tabatznik & Isaacs, 1961); as a result of drug therapy (Costa, Holland & Pickren, 1961;Shafar, 1965) and with penicillin hypersensitivity (Schoenwetter & Silber, 1965), the clinical features are the same. This suggests that an autoimmunity reaction rather than direct causation by all the various agents may be responsible.…”

Acute non-specific pericarditis

“…Furthermore, an identical clinical picture of acute non-specific pericarditis can be seen following other infections such as Reiter's disease (Csonka & Oates, 1957), infectious mononucleosis (Gardner, 1959) and lymphogranuloma venereum (Sheldon et al, 1948). Likewise in pericarditis following heart operations (Engle & Ito, 1961); following myocardial infarction (Dressler, 1959a); gunshot wounds to the heart (Wood, 1956); following traumatic haemopericardium (Tabatznik & Isaacs, 1961); as a result of drug therapy (Costa, Holland & Pickren, 1961;Shafar, 1965) and with penicillin hypersensitivity (Schoenwetter & Silber, 1965), the clinical features are the same. This suggests that an autoimmunity reaction rather than direct causation by all the various agents may be responsible.…”

Συνθεση Και Φαρμακοχημικη Μελετη Παραγωγων Θειαζολιου Με Βιολογικο Ενδιαφερον

“…Στους ηλικιωμέ νους ασθενείς τα ΜΣΑΦ όπως η ναπροξένη ή η ιμπουπροφαίνη προ καλούν διαταραχές της αναγνώρισης και αμνησία [195]. ζ) Τα ΜΣΑΦ μπορούν να προκαλέσουν διαταραχές και σε άλλα συστήμα τα του οργανισμού [196][197][198].…”