Pheochromocytoma and Multiple Endocrine Neoplasia

Reusch, Claudia E

doi:10.1016/b978-1-4557-4456-5.00013-4

Cited by 24 publications

(59 citation statements)

References 146 publications

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“…From the first survey, it emerged that two thirds of radiologists currently do not perform FNAs of adrenal masses because of concern of potential adverse reactions. Although studies on the subject are limited with a paucity of significant data, the procedure is still not recommended or to be performed with caution …”

Section: Discussionmentioning

confidence: 99%

“…Signalment, main clinical signs, and selected clinicopathological findings such as the presence of stress leukogram, thrombocytosis, increased alkaline phosphatase (ALP), and urinary specific gravity, the presence of proteinuria (through urinary protein:urinary creatinine ratio), endogenous ACTH concentrations, results of an ACTH stimulation test or of a low‐ or high‐dose dexamethasone suppression test, systemic blood pressure before, during and after the FNA procedure, and measurements of urinary normetanephrine/urinary creatinine or serum metanephrine concentrations were collected in an excel spreadsheet if available and evaluated. The review of the medical records was mainly aimed at obtaining useful information for a diagnosis of cortisol producing or catecholamine producing adrenal tumor …”

Section: Methodsmentioning

confidence: 99%

“…Potential differential diagnoses also include macronodular hyperplasia, cysts, granuloma, hematoma, and myelolipomas . Following adrenal lesion detection, it is crucial to determine its potential functionality (secreting versus nonsecreting), its origin (epithelial or neuroendocrine), its biological nature (malignant or benign), and its connection with adjacent vessels/organs . History, clinical signs, clinicopathological findings, endocrine tests and US, contrast‐enhanced US, and CT can assist in predicting the functional aspect of an adrenal lesion and in differentiating between a benign and malignant process.…”

Section: Introductionmentioning

confidence: 99%

“…Several situations might complicate the diagnostic approach. Secretory masses, in particular pheochromocytoma, can produce an insufficient amount of hormone and therefore less characteristic clinical signs and equivocal endocrine testing . This confuses their identity with that of a nonsecretory tumor.…”

Section: Introductionmentioning

confidence: 99%

“…However, performing percutaneous US-guided FNA of adrenal lesions is controversial and remains an important debate in veterinary medicine. [4][5][6][7] The risk of hypertensive crisis discourages veterinarians from the procedure, [4][5][6][7] although evidence is only based on reports in the human literature. [8][9][10][11] In veterinary medicine, risk assessment is anecdotal.…”

mentioning

confidence: 99%

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Safety of percutaneous ultrasound‐guided fine‐needle aspiration of adrenal lesions in dogs: Perception of the procedure by radiologists and presentation of 50 cases

Pey

Diana

Rossi

et al. 2020

Veterinary Internal Medicne

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Background Percutaneous ultrasound (US)‐guided fine‐needle aspiration (FNA) of adrenal gland lesions is controversial in veterinary medicine. Objective To evaluate the frequency and radiologists' perception of the risk of the procedure as well as determining the incidence of complications. Methods Retrospective study. A first survey was submitted by e‐mail to all board‐certified radiologists of the American College of Veterinary Radiology (ACVR) and European College of Veterinary Diagnostic Imaging (ECVDI). A second survey was sent to radiologists who declared having performed the procedure at least once in their career (observational cross‐sectional case study). Results The first survey was sent to 977 diplomates and answered by 138. Of 138 diplomates, 40 currently performed the procedure and 98 did not; 44 of the 98 gave the hypertensive crisis risk in pheochromocytoma as a reason. To the second survey, 12 of 65 responded positively; 50 dogs with 58 lesions were recruited, including 23 pheochromocytomas. Complications were reported in 4 of 50 dogs; 3 hemorrhages (1 mild and 1 moderate) and 1 death from acute respiratory distress syndrome (possibly related to laryngeal paralysis). No hypertensive crisis was reported. There was no relationship between the method of FNA/type of needle used and occurrence of complications. Based on the recollection of these 65 radiologists, who performed approximately 200 FNA of adrenal lesions, a death rate of approximately 1% was estimated. Conclusions and Clinical Importance Percutaneous US‐guided FNA of adrenal lesions can be considered a minimally risky procedure, despite the negative perception by radiologists.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%