Pheochromocytoma in Indian patients: A retrospective study

Krishnappa, R; Chikaraddi, SB; Arun, H N; Deshmane, Vijayalakshmi

doi:10.4103/0019-509x.98951

Cited by 7 publications

(6 citation statements)

References 21 publications

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“…In the literature, there is almost no mortality, thanks to the progress of medical imaging and biology, which allow preoperative diagnosis [4,19].…”

Section: Discussionmentioning

confidence: 99%

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Ectopic pheochromocytoma or paraganglioma of the ZUCKERKANDL organ: A case report and review of the literature

Zongo

Koama

Kambou

et al. 2019

International Journal of Surgery Case Reports

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Highlights EPIDEMIOLOGY : paraganglioma of the ZUCKERKANDL organ is a rare neuroendocrine tumour but must be known. DIAGNOSIS : The typical presentation which is the Menard Triad of symptoms, associating headaches, sweating and palpitation. Preoperative diagnosis can be difficult in pauci-symptomatic cases. The Clinical signs, Abdominal-pelvic CT scan and biology are the steps of the preoperative diagnosis. TREATMENT : Treatment is surgical. Preoperative medical preparation is aimed at reducing risks of peroperative hemodynamic instability. The anesthetist should therefore prepare himself to manage blood pressure peaks during the tumour’s dissection, but also the possible low blood pressure at the end of exeresis. Surgery remains the key element of treatment and consists in exeresis of the paragaglioma. PROGNOSIS : paraganglioma of the ZUCKERKANDL organ is often a benign tumor. The resuscitation determines the patient’s prognosis.

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“…In the literature, there is almost no mortality, thanks to the progress of medical imaging and biology, which allow preoperative diagnosis [4,19].…”

Section: Discussionmentioning

confidence: 99%

“…Treatment is surgical and requires a careful medical preparation [3]. Throughout its evolution there may be recurrences, but the outcome is most often favourable [4]. Despite their scarcity, European western literature of pheochromocytomas is rich.…”

Section: Introductionmentioning

confidence: 99%

Ectopic pheochromocytoma or paraganglioma of the ZUCKERKANDL organ: A case report and review of the literature

Zongo

Koama

Kambou

et al. 2019

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

show abstract

“…Clinical features may be vague, posing a diagnostic problem, and include abdominal pain, hypertension,[ 4 ] headache, anxiety, sweating, palpitations, syncope, nausea, and vomiting. Patients may experience paradoxical response to beta-blockade and ischemic cardiac pain in the absence of coronary disease due to coronary spasm.…”

Section: Discussionmentioning

confidence: 99%

The unexpected diagnosis of phaeochromocytoma in the anaesthetic room

et al. 2018

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A 77-year-old man was admitted for aortic valve replacement and combined coronary bypass grafting. Grossly, labile arterial pressures were demonstrated on anesthetic induction prompting cancellation and Intensive Care Unit transfer. Urine analysis identified high normetadrenaline/creatinine ratio, plasma metanephrine, and plasma normetanephrine. A left adrenal lesion on computed tomography scan collectively indicated pheochromocytoma. Laparoscopic adrenalectomy was prioritized at multidisciplinary team before cardiac surgery. Vague symptoms of pheochromocytoma pose a diagnostic problem, being often attributed to common/co-existing pathology. The blood pressure instability on anesthetic required precise control, multidisciplinary input, and awareness of possible diagnosis as a routine intervention for hypotension may have been fatal in view of underlying cardiac pathology.

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“…It includes various disorders in the form of adrenal insufficiency, Cushing syndrome (CS), secondary hypertension (pheochromocytoma and Conn's syndrome), and congenital adrenal hyperplasia (CAH) which are treatable and have avoidable morbidity and mortality. [12345] In India, diseases affecting the adrenal glands are an example of environmentally induced endocrine diseases. Hence, infection is the most common cause of adrenal insufficiency in India.…”

Section: Introductionmentioning

confidence: 99%

Study of awareness of adrenal disorders among interns and postgraduate students of Hamidia Hospital, Bhopal

Chittawar

Dubey

Sharma

et al. 2017

Indian J Endocr Metab

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Introduction:Adrenal disorders could be a life-threatening emergency, hence requires immediate therapeutic management. For this awareness regarding its diagnosis, management, and treatment is prime important.Aims and Objective:To study the awareness of adrenal disorders among interns and postgraduates students of Hamidia Hospital, Bhopal.Materials and Methods:A cross-sectional questionnaire-based study was performed. Fifty-six participants, i.e., 1st, 2nd, and 3rd years postgraduate residents of general medicine (n = 14 × 3) and interns (n = 14) were included in the study. There were 12 questions on adrenal insufficiency, adrenal adenoma, congenital adrenal hyperplasia (CAH), nonclassical CAH (NCCAH), pheochromocytoma, and Conn's syndrome. One mark was awarded for each correct response.Results:In the present study, 14 (25%) participants scored < 5 marks, 33 (58.9%) scored between 6 and 9, and 9 (16.1%) scored between 10 and 12. The mean score among the participants was 6.38 ± 2.505, with a range from 2 to 11 marks. The number of correct answers by postgraduates residents of 1st year was 101, 2nd year was 95, and 3rd year was 93 and interns scored 68 out of total 168 questions in each group. Mean awareness score for residents of 1st, 2nd, 3rd years participants and interns was 7.21 ± 2.806, 6.79 ± 2.119, and 6.64 ± 2.818 and 6.63 ± 2.505, respectively. Most of the participants recorded correct responses related to diagnosis (57.7%) followed by responses related to treatment (64.3%). Answers to a question regarding how commonly is adrenal insufficiency diagnosed in medical Intensive Care Unit, none of the individuals responded correctly.Conclusion:There was a lack of awareness regarding diagnosis, management, and treatment of adrenal disorders in central India. We need to prioritize training related to these illnesses in our postgraduate teaching curriculum in practice.

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Pheochromocytoma in Indian patients: A retrospective study

Cited by 7 publications

References 21 publications

Ectopic pheochromocytoma or paraganglioma of the ZUCKERKANDL organ: A case report and review of the literature

Ectopic pheochromocytoma or paraganglioma of the ZUCKERKANDL organ: A case report and review of the literature

The unexpected diagnosis of phaeochromocytoma in the anaesthetic room

Study of awareness of adrenal disorders among interns and postgraduate students of Hamidia Hospital, Bhopal

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