Pheochromocytoma mimicking (or triggering?) takotsubo cardiomyopathy and hypertrophic cardiomyopathy

Polymorphic tachycardia in an anaesthetised horse with an undiagnosed pheochromocytoma undergoing emergency coeliotomy

“…Both determinants of cardiac output (stroke volume, HR) and thus peripheral perfusion were affected in this horse. Some components influencing stroke volume (preload and contractility) were reduced from haemorrhage, hypovolaemia, anaesthetics, and hypothetical cardiomyopathy due to pheochromocytoma 14. Eventually, the persistent increase in HR shortened the diastolic filling time and thus stroke volume and contributed to an overall decreased cardiac output.…”

“…Some components influencing stroke volume (preload and contractility) were reduced from haemorrhage, hypovolaemia, anaesthetics, and hypothetical cardiomyopathy due to pheochromocytoma. 14 Eventually, the persistent increase in HR shortened the diastolic filling time and thus stroke volume and contributed to an overall decreased cardiac output. Factors which in the present case could have favoured the development of tachycardia and paroxysmal polymorphic tachyarrhythmias are hypoxia, 15 hypercapnia 16 17 acidosis, 18 severe hyperlactataemia, sympathetic stimulation, 16 17 and low stroke volume and hypotension.…”

Pheochromocytoma-related cardiomyopathy presenting as broken heart syndrome: Case report and literature review

“…There is a recently-growing body of literature on a minority of pheochromocytoma patients who present in overt cardiogenic shock from a catecholamine-induced cardiomyopathy [[2], [3], [4], [5], [6], [7], [8], [9]]. On cardiac catheterization and echocardiography, apical ballooning is a common feature that leads many to diagnose takotsubo syndrome, also known as broken heart syndrome, a stress-induced cardiomyopathy.…”