Pheochromocytoma of the Urinary Bladder – A Case Report of an Unusual Presentation

Nerli, Rajendra B; Magdum, Prasad V.; Patil, Amey Y.; Devraju, Shishir; Hiremath, Murigendra B

doi:10.1007/s13193-015-0430-z

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…Pheochromocytomas can occur anywhere from the skull to the bladder, and around 10% arise from extra -adrenal organs, where they are known as paragangliomas (2) . Bladder pheochromocytoma arises from the chromaffin tissue of the sympathetic nervous system and is associated with the bladder wall (3) . It accounts for less than 0.06% of all bladder tumors and less than 1% of all pheochromocytomas (4) .…”

Section: Introductionmentioning

confidence: 99%

Magnetic resonance imaging of bladder pheochromocytoma: A case report

Qin

Wang²,

Du³

et al. 2022

Int J Radiat Res

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Bladder pheochromocytoma, as a rare bladder tumor, which originated from the chromaffin tissue of the sympathetic nervous system. It is difficult to distinguish from other non-epithelial tumors on imaging. This study reported a 31-year-old female, whose physical examination revealed a bladder mass for 50 days. The patient's main clinical symptoms included sudden headache, dizziness, increased blood pressure, and chest palpitations after intermittent micturition. However, laboratory tests showed that the 24-hour urine catecholamine levels (norepinephrine, vanillylmandelic acid [VMA] and metanephrine) were normal. Magnetic resonance imaging (MRI) showed a mass in the posterior bladder wall, the typical performance is"light-bulb" bright lesion on T2-weighted imaging. The mass was surgically excised, and histopathological examination revealed that it was a pheochromocytoma. During the first 3-month of postoperative follow-up, the patient's symptoms gradually subsided. To our knowledge, this is the first case reporting on the use of MRI imaging and specific image features of this rare bladder pheochromocytoma. Due to the better soft tissue resolution and multi-parameter on MRI, changes in the size and internal signal of the lesion can be clearly displayed. Thus, MRI is an indispensable tool in tumor diagnosis and prognosis assessment.

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Section: Introductionmentioning

confidence: 99%

Magnetic resonance imaging of bladder pheochromocytoma: A case report

Qin

Wang²,

Du³

et al. 2022

Int J Radiat Res

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Paraganglioma (pheochromocytoma) of the urinary bladder: A systematic review with a diagnostic, management and treatment algorithm

Hooshyari

Tyson

Rice

2022

Journal of Clinical Urology

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Introduction: Paraganglioma of the urinary bladder is a rare but well-documented tumour. Herein, we provide the largest, comprehensive systematic review of the literature and aim to increase familiarity with this rare but significant neoplasm. Methods: A systematic review of the literature was conducted on the NCBI PubMed database. The search criteria were not limited to any specific years or languages. There were 418 articles between January 1953 and August 2020, of which 255 case reports were selected. Results: Paragangliomas of the urinary bladder most commonly occurred in Caucasians in the fifth decade of life, most commonly presenting with haematuria and variations of ‘micturition attacks’. Eighty percent of tumours were functionally active. The mucosa was normal in 91% of patients. In all, 25% of tumours were treated with transurethral resection alone, 65% had partial cystectomy and 5% had radical cystectomy. Alpha-blockers were administered pre-operatively in 38% of patients and the risk of intra-operative hypertensive crisis was over three times greater in those who did not receive an alpha-blocker. The tumour was confined to the bladder in 75% of cases. Metastasis occurred in 20% of cases, most commonly to iliac nodes. The mean follow-up time was 26.5 months. In cases that documented follow-up, 18.6% had recurrence, most commonly in lymph nodes and bone. Conclusion: All patients presenting with micturition attacks or haematuria with a computed tomography showing an enhancing, well-defined submucosal bladder lesion and/or cystoscopy showing a lesion with normal overlying mucosa should be worked up for a possible paraganglioma of the urinary bladder. Level of evidence: Not applicable

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Pheochromocytoma of the Urinary Bladder – A Case Report of an Unusual Presentation

Abstract: Urinary bladder pheochromocytoma is rare. We report a case of bladder pheochromocytoma presenting with practically no obvious clinical symptoms in an adolescent who had undergone repair of mitral valve disease.

Cited by 2 publications

References 4 publications

Magnetic resonance imaging of bladder pheochromocytoma: A case report

Magnetic resonance imaging of bladder pheochromocytoma: A case report

Paraganglioma (pheochromocytoma) of the urinary bladder: A systematic review with a diagnostic, management and treatment algorithm

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