Phlegmasia cerulea dolens: a swelling, cyanosis and discolouration of the extremity in the ICU

Alves, João; Salgueiro, Andrea; Baptista, João Pedro; Coimbra, Paulo

doi:10.1136/bcr-2022-251973

Cited by 1 publication

(1 citation statement)

References 11 publications

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“…Critically ill patients often have multiple PCD susceptibility factors such as hypercoagulation, heart failure, and trauma, which is a rare condition leading to severe limb ischemia, caused by early arterial flow obstruction secondary to extensive deep vein thrombosis [17]. Subsequently, the author searched through Pub again with the keywords "Intensive Care Unit, phlegmasia cerulea dolens", which only found a few related articles mentioning that COVID-19 infection was associated with the onset of the disease, which was linked with significant venous thromboembolism after neocoronavirus infection [18] [19].…”

Section: Literature Reviewmentioning

confidence: 99%

Analysis and Literature Review of Deep Vein Thrombosis Related Phlegmasia Cerulea Dolens Diagnosis in Critically Patients

Zhang,

Yang,

Chang

2023

CRCM

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Goal: The purpose of this research is to analyze the clinical characteristics, diagnosis, treatment, and prognosis of critical care patients with phlegmasia cerulea dolens (PCD) caused by deep vein thrombosis. Our goal is to improve both awareness and early diagnosis and treatment of rare clinical diseases. Furthermore, we aim to examine advancements in the diagnosis and treatment of deep vein thrombosis. Method: The clinical information of patients with PCD received in 2022 was subject to retrospective analysis. The author conducted a search of 191 publications with a focus on PCD, from January 2010 to July 2022, from databases such as the China National Knowledge Infrastructure (CNKI), Wanfang Data, PubMed, etc. The results were used to summarize the examinations, diagnostic criteria, and treatment progress of PCD patients. Additionally, the author conducted another search using keywords such as "Venous thromboembolism" and "Anticoagulant drugs" to summarize research progress in anticoagulant drugs and the treatment of VTE. The search was limited to relevant. Outcome: Six months prior to admission, the patient, a 68-year-old female, developed sunken edema and cyanosis in both her lower extremities and was diagnosed with lower extremity deep vein thrombosis complicated by PCD, lower extremity ischemic necrosis, and septicemia. This diagnosis was made using a combination of CT and lower extremity vascular ultrasound-related examinations, as well as a significantly elevated D-dimer value. Despite active treatment and aggressive measures, such as anti-infection, organ function maintenance, anticoagulation, and improvement of microcirculatory disorders, the patient's family declined corresponding surgical treatment and interventional surgery for the lower extremity due to objective factors, and the patient ultimately succumbed to her illness. The clinical characteristics of this patient were similar to those of How to cite this paper: Zhang, Q., Yang, L. and Chang, L. (2023) Analysis and Literature Review of Deep Vein Thrombosis Related Phlegmasia Cerulea Dolens Diagnosis in Critically Patients. Case Reports in Clinical Medicine, 12, 312-323.

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Section: Literature Reviewmentioning

confidence: 99%