Phlyctenular conjunctivitis: a rare association with spinal intramedullary tuberculoma

Bhandari, Aveg; Bhandari, Heena; Shukla, Rakesh; Giri, Prithvi

doi:10.1136/bcr-2013-202010

Cited by 8 publications

(2 citation statements)

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“…In this patient, the disease involved the spinal cord after the onset of tubercular meningitis for 2 mo. There have been a few case reports describing intramedullary suppurative and subdural abscesses[ 8 ]. The postoperative pathological examination in this case revealed many neutrophils in the lesion as well as granulation tissue formation, indicating the trend of suppurative inflammation and abscess formation.…”

Section: Discussionmentioning

confidence: 99%

Paraplegia from spinal intramedullary tuberculosis: A case report

Qu¹,

Wu²,

Guo³

et al. 2020

WJCC

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BACKGROUND Tuberculosis (TB) mostly attacks the lungs, and extrapulmonary TB involving the central nervous system is uncommon; among these cases, spinal intramedullary TB is even more rare. The clinical manifestations of spinal intramedullary TB are similar to those of intramedullary spinal cord tumors. Therefore, it is necessary to make a careful differential diagnosis of spinal intramedullary lesions to achieve the appropriate treatment and favorable prognosis. We report a rare case of a young male patient with paraplegia due to spinal intramedullary TB, which is uncommon and regrettable. CASE SUMMARY A 23-year-old male presented with fever accompanied by nausea and vomiting lasting for 2 mo and was then diagnosed with tubercular meningitis. After anti-TB treatment, his symptoms were significantly improved. However, 2 mo after the diagnosis of tubercular meningitis, the patient felt numbness below the costal arch level, which lasted for 1 wk, and he paid no attention to this symptom. What followed was paraplegia and urine/fecal incontinence. Magnetic resonance imaging of the thoracic spine showed a ring-enhanced intramedullary cord lesion at T8-T9. Lesion exploration showed enlargement of the spinal cord at T8-T9, and the lesion could be observed by incision. The lesion was adhered to the peripheral tissue and was grayish-white and tough with a poor blood supply and a diameter of approximately 0.8 cm. The lesion was resected completely. The results of pathological examination by both hematoxylin-eosin staining and acid-fast bacilli staining confirmed TB, accompanied by acute and chronic suppurative inflammation and granulation tissue formation. The patient was instructed to continue anti-TB treatment after the operation, but he did not follow the medical advice. Follow-up continued for ten years, the patient had persistent paraplegia, the numbness disappeared and urine/fecal sensation recovered. CONCLUSION Although TB is a kind of benign disease, some cases progress rapidly. Moreover, spinal intramedullary TB may seriously endanger quality of life and still needs timely diagnosis and proper treatment.

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Section: Discussionmentioning

confidence: 99%

Paraplegia from spinal intramedullary tuberculosis: A case report

Qu¹,

Wu²,

Guo³

et al. 2020

WJCC

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“…It is relatively more common in the paediatric age group in association with pulmonary and lymph node tuberculosis. 1 Many antigens like staphylococcal products, worm infestation, fungi, viruses, and parasites but the main antigen responsible for PKC was tuberculoprotein. [2][3][4][5][6] We report a case of PKC in a patient who was Mantoux test positive but no other clinical features of tuberculosis.…”

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confidence: 99%