2006
DOI: 10.1104/pp.106.079707
|View full text |Cite
|
Sign up to set email alerts
|

PHO2, MicroRNA399, and PHR1 Define a Phosphate-Signaling Pathway in Plants

Abstract: Inorganic phosphate (Pi)-signaling pathways in plants are still largely unknown. The Arabidopsis (Arabidopsis thaliana) pho2 mutant overaccumulates Pi in leaves in Pi-replete conditions. Micrografting revealed that a pho2 root genotype is sufficient to yield leaf Pi accumulation. In pho2 mutants, Pi does not repress a set of Pi starvation-induced genes, including AtIPS1, AT4, and Pi transporters Pht1;8 and Pht1;9. Map-based cloning identified PHO2 as At2g33770, an unusual E2 conjugase gene. It was recently sho… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

77
1,267
4
19

Year Published

2009
2009
2016
2016

Publication Types

Select...
5
3

Relationship

0
8

Authors

Journals

citations
Cited by 1,035 publications
(1,367 citation statements)
references
References 48 publications
(76 reference statements)
77
1,267
4
19
Order By: Relevance
“…2A-B). This result indicates that miR399 targeting of PHO2 is conserved across angiosperms (Bari et al, 2006), including maize.…”
Section: Analysis Of Mirnas and Their Targetsmentioning
confidence: 75%
See 2 more Smart Citations
“…2A-B). This result indicates that miR399 targeting of PHO2 is conserved across angiosperms (Bari et al, 2006), including maize.…”
Section: Analysis Of Mirnas and Their Targetsmentioning
confidence: 75%
“…Another two miRNAs involved in the control of normal leaf growth and development were altered by the abiotic stress treatments miR166 and miR396 (Nogueira et al, 2007;Liu et al, 2009). MiR399 controls inorganic phosphate (Pi) homeostasis and its response to Pi is highly specific (Bari et al, 2006). Nonetheless, we detected miR399 down-regulation in the wild-type shoot apical meristematic area during drought stress and in the leaf of rmr6-1 plants during the combined stress.…”
Section: Long-term Abiotic Stresses Affect Accumulation Of Very Few Mmentioning
confidence: 76%
See 1 more Smart Citation
“…Some transcription factors have specifically been associated with the response to P deprivation. They include OsPTF1 (Os06g09370), which has been reported to contribute to tolerance to inorganic phosphate starvation (Yi et al 2005), the "phosphate-induced protein" (phi-1; Os02g52040), and the "phosphate starvation response" factors (PHR1, Os03g21240; PHR2, Os07g25710) that form a regulatory circuit with PHO2 (Os06g40500) and micro-RNA399 (Fang et al 2008;Bari et al 2006). All were only regulated by the factor E and only in shoots.…”
Section: Transcription Factorsmentioning
confidence: 99%
“…Located downstream of PHR1, miR399 and IPS1 (induced by phosphate starvation1) are specifically induced by −P stress. The miR399 reciprocally regulates the expression of PHO2/UBC24 and the resulting protein functions as an ubiquitin-conjugating E2 enzyme (Bari et al 2006). A loss of function of PHO2/UBC24 could lead to excessive Pi accumulation in the shoot (Fujii et al 2005).…”
Section: Introductionmentioning
confidence: 99%