2011
DOI: 10.1007/s10165-011-0441-8
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Phonoarthrography, musculoskeletal ultrasonography, and biochemical biomarkers for the evaluation of knee cartilage in osteoarthritis

Abstract: The aim of this study was to examine the relationship among three different parameters used to assess cartilage in osteoarthritis (OA) of the knee. These parameters are phonoarthrography (Phono-A), musculoskeletal ultrasonography (MSUS) from the 4 condyles, and biochemical markers; notably, matrix metalloproteinase-3 (MMP-3) and tissue inhibitor of proteinase (TIMP-1). A total of 100 knees with chronic idiopathic OA diagnosed according to the American College of Rheumatology (ACR) criteria were studied, togeth… Show more

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Cited by 11 publications
(6 citation statements)
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“…A more recent study showed that MMP-3 rises in the early and middle grades of knee OA. 1 In our study, MMP3 was shown to be significantly elevated in the OA group.…”
Section: Discussionsupporting
confidence: 54%
“…A more recent study showed that MMP-3 rises in the early and middle grades of knee OA. 1 In our study, MMP3 was shown to be significantly elevated in the OA group.…”
Section: Discussionsupporting
confidence: 54%
“…Many studies have shown that serum MMP3 levels are higher in OA patients than in healthy people (13)(14)(15)(16)(17), and we observed that serum MMP3 levels were considerably higher in knee OA patients than in healthy people.…”
Section: Discussionsupporting
confidence: 49%
“…Several reports have described elevations of MMP‐1 and MMP‐3 in human patients, with OA affecting a variety of joints and with different severity . Particular MMP have been identified in higher concentrations in synovial fluid of osteoarthritic joints compared with normal joints and remain elevated for long periods of time in injured joints, thus having the potential to be reliable indicators of joint environment changes after treatment .…”
Section: Discussionmentioning
confidence: 99%