We present the first observation of optomechanical coupling in ultra-high Q crystalline whisperinggallery-mode (WGM) resonators. The high purity of the crystalline material enables optical quality factors in excess of 10 10 and finesse exceeding 10 6 . Simultaneously, mechanical quality factors greater than 10 5 are obtained, still limited by clamping losses. Compared to previously demonstrated cylindrical resonators, the effective mass of the mechanical modes can be dramatically reduced by the fabrication of CaF2 microdisc resonators. Optical displacement monitoring at the 10 −18 m/ √ Hzlevel reveals mechanical radial modes at frequencies up to 20 MHz, corresponding to unprecedented sideband factors (> 100). Together with the weak intrinsic mechanical damping in crystalline materials, such high sindeband factors render crystalline WGM micro-resonators promising for backaction evading measurements, resolved sideband cooling or optomechanical normal mode splitting. Moreover, these resonators can operate in a regime where optomechanical Brillouin lasing can become accessible.PACS numbers: 42.65. Sf, 42.50.Wk Optical interferometers with suspended mirrors have traditionally been key elements in gravitational wave detectors. Implemented at a mesoscopic scale ( 1 cm), micro-and nano-scale physical systems coupling optical and mechanical degrees of freedom may allow studying optomechanical coupling at the quantum level [1,2]. In particular, recent experiments have aimed towards the observation of measurement quantum backaction [4,5] and radiation-pressure cooling of a mesoscopic mechanical oscillator to its quantum ground state [6][7][8]. However, inevitable coupling of the system to its environment severely impedes such studies. For example, thermal fluctuations associated with mechanical dissipation mask the signatures of quantum backaction [3][4][5], but also constitute a mechanism competing with radiation-pressure cooling [6][7][8]. Optical losses, on the other hand, destroy potential quantum correlations [4], give rise to heating due to the absorbed photons [6], and preclude reaching the important resolved-sideband regime [9]. Most of the various optomechanical systems investigated recently are based on amorphous material such as SiO 2 [9, 10] or Si 3 N 4 [8,11,12]. The absence of microscopic order makes these materials prone to mechanical losses due to coupling of strain fields to two-level systems (TLS) [13,14], particularly severe at cryogenic temperatures [15]. Strained Si 3 N 4 oscillators have achieved higher mechanical quality factors Q m ≈ 1 × 10 7 , however, optical finesse (F) has been limited to values below 10 4 [11,12], although the imaginary part of the refractive index can be lower than 10 −5 [12]. Crystalline materials, in contrast, do not suffer from such restrictions at all. In fact, the best optical resonators available today are whisperinggallery mode (WGM) resonators made from CaF 2 , featuring F up to 10 7 [16][17][18][19]. At the same time, due to their long range order, crystalline mate...