Phosphoinositide signaling in plant development

Heilmann, Ingo

doi:10.1242/dev.136432

Cited by 138 publications

(146 citation statements)

References 129 publications

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“…In Arabidopsis , the major PA molecular species, including 34:2, 34:3, and 36:5, increased compared with its control after salt treatment (Yu et al, ). PI is the precursor of phosphoinositides, which serve as signaling molecules and have involvement in membrane trafficking processes (Heilmann, ; Hou, Ufer, & Bartels, ). Phosphoinositides could regulate ion channels, including potassium channels, affecting nutrient uptake and transport (Hille, Dickson, Kruse, Vivas, & Suh, ).…”

Section: Discussionmentioning

confidence: 99%

Up‐regulation of lipid metabolism and glycine betaine synthesis are associated with choline‐induced salt tolerance in halophytic seashore paspalum

Gao

Zhang

et al. 2019

Plant Cell & Environment

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Choline may affect salt tolerance by regulating lipid and glycine betaine (GB) metabolism. This study was conducted to determine whether alteration of lipid profiles and GB metabolism may contribute to choline regulation and genotypic variations in salt tolerance in a halophytic grass, seashore paspalum (Paspalum vaginatum). Plants of Adalayd and Sea Isle 2000 were subjected to salt stress (200‐mM NaCl) with or without foliar application of choline chloride (1 mM). Genotypic variations in salt tolerance and promotive effects of choline application on salt tolerance were associated with both the up‐regulation of lipid metabolism and GB synthesis. The genotypic variations in salt tolerance associated with lipid metabolism were reflected by the differential accumulation of phosphatidylcholine and phosphatidylethanolamine between Adalayd and Sea Isle 2000. Choline‐induced salt tolerance was associated with of the increase in digalactosyl diacylglycerol (DGDG) content including DGDG (36:4 and 36:6) in both cultivars of seashore paspalum and enhanced synthesis of phosphatidylinositol (34:2, 36:5, and 36:2) and phosphatidic acid (34:2, 34:1, and 36:5), as well as increases in the ratio of digalactosyl diacylglycerol: monogalactosyl diacylglycerol (DGDG:MGDG) in salt‐tolerant Sea Isle 2000. Choline regulation of salt tolerance may be due to the alteration in lipid metabolism in this halophytic grass species.

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Section: Discussionmentioning

confidence: 99%

Up‐regulation of lipid metabolism and glycine betaine synthesis are associated with choline‐induced salt tolerance in halophytic seashore paspalum

Gao

Zhang

et al. 2019

Plant Cell & Environment

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“…The very low abundant phosphoinositides (PIs) are important players for the recruitment of peripheral proteins to membranes (Balla, 2013;Heilmann, 2016). PIs are mono-, bis-and tris-phosphorylated derivatives of phosphatidylinositol (PtdIns) and PI compositions differ between the plasma membrane and different organellar membranes (Balla, 2013).…”

Section: Introductionmentioning

confidence: 99%

Phospholipid composition and a polybasic motif determine D6 PROTEIN KINASE polar association with the plasma membrane and tropic responses

et al. 2016

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Polar transport of the phytohormone auxin through PIN-FORMED (PIN) auxin efflux carriers is essential for the spatiotemporal control of plant development. The Arabidopsis thaliana serine/threonine kinase D6 PROTEIN KINASE (D6PK) is polarly localized at the plasma membrane of many cells where it colocalizes with PINs and activates PIN-mediated auxin efflux. Here, we show that the association of D6PK with the basal plasma membrane and PINs is dependent on the phospholipid composition of the plasma membrane as well as on the phosphatidylinositol phosphate 5-kinases PIP5K1 and PIP5K2 in epidermis cells of the primary root. We further show that D6PK directly binds polyacidic phospholipids through a polybasic lysine-rich motif in the middle domain of the kinase. The lysine-rich motif is required for proper PIN3 phosphorylation and for auxin transport-dependent tropic growth. Polybasic motifs are also present at a conserved position in other D6PK-related kinases and required for membrane and phospholipid binding. Thus, phospholipid-dependent recruitment to membranes through polybasic motifs might not only be required for D6PK-mediated auxin transport but also other processes regulated by these, as yet, functionally uncharacterized kinases.

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“…This distribution patterns at least to some extent coincide with the subcellular localization of the individual kinases catalyzing PI-synthesis and the phenotypes of the respective knock-out mutants [234,235]. Overall, the general conclusion is that the delivery/retrieval of vesicles to and from the PM is accompanied with a progressively increasing degree of phosphorylation (PtdIns→PtdIns4P→PtdIns(4,5)P 2 ) in subsequent membranes [234]. It appears that PIs in plants are also involved in controlling the central machinery for membrane trafficking and protein sorting.…”

Section: Secretory Trafficking Pathwaymentioning

confidence: 81%

“…Analysis with fluorescent probes specific for particular species of PtdIns revealed that PtdIns(4,5)P 2 is predominantly present in the PM at the tip of growing root hairs upon salt stress, PtdIns3P in motile membranous structures, or tonoplast and PtdIns4P in the TGN and the PM [231,232,233]. This distribution patterns at least to some extent coincide with the subcellular localization of the individual kinases catalyzing PI-synthesis and the phenotypes of the respective knock-out mutants [234,235]. Overall, the general conclusion is that the delivery/retrieval of vesicles to and from the PM is accompanied with a progressively increasing degree of phosphorylation (PtdIns→PtdIns4P→PtdIns(4,5)P 2 ) in subsequent membranes [234].…”

Section: Secretory Trafficking Pathwaymentioning

confidence: 99%

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Annexins as Overlooked Regulators of Membrane Trafficking in Plant Cells

Konopka-Postupolska

Clark

2017

IJMS

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Annexins are an evolutionary conserved superfamily of proteins able to bind membrane phospholipids in a calcium-dependent manner. Their physiological roles are still being intensively examined and it seems that, despite their general structural similarity, individual proteins are specialized toward specific functions. However, due to their general ability to coordinate membranes in a calcium-sensitive fashion they are thought to participate in membrane flow. In this review, we present a summary of the current understanding of cellular transport in plant cells and consider the possible roles of annexins in different stages of vesicular transport.

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Phosphoinositide signaling in plant development

Cited by 138 publications

References 129 publications

Up‐regulation of lipid metabolism and glycine betaine synthesis are associated with choline‐induced salt tolerance in halophytic seashore paspalum

Up‐regulation of lipid metabolism and glycine betaine synthesis are associated with choline‐induced salt tolerance in halophytic seashore paspalum

Phospholipid composition and a polybasic motif determine D6 PROTEIN KINASE polar association with the plasma membrane and tropic responses

Annexins as Overlooked Regulators of Membrane Trafficking in Plant Cells

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