Phospholipid monolayers of di-oleoyl lecithin (di-O-PC) at the mercury/water interface

The Electrochemistry of Liposomes

“…These authors studied the blocking effect of adsorbed lecithin monolayers on the mercury electrode and related it to the transport of ions across the membrane, 99,101 gained insight into the structure and properties of the adsorbed monolayer with the help of electrochemical measurements, like AC voltammetry and cyclic voltammetry, 100,102,103 and determined the effect of foreign molecules on the properties of the monolayer using also electrochemical methods 104,105 . Work in this direction of research was expanded by Nelson and coworkers, who studied the behavior of adsorbed monolayers in an electric field 106–111 as well as the effect of the inclusion of foreign molecules, like the channel‐forming gramicidin in the adsorbed phospholipid monolayer using voltammetric 112–115 as well as impedance, 116,117 chronoamperometric, 118,119 and chronocoulometric measurements 120 . Mainly the blocking effect and how it changes according to the conditions, and for different membrane‐modifying molecules and electroactive species, were studied using these methods.…”

Electrochemical and spectroelectrochemical characterization of lipid organization in an electric field

“…The transfer of lipid onto a Hg drop electrode, the inhibiting characteristics of these layers towards ion or oxygen transport, and the effect of protein penetration into these lipid layers were investigated using CV, capacitance and radiochemical labelling. This procedure was adopted by Nelson and co-workers [52,[69][70][71][72][73][74][75][76][77][78][79][80][81][82][83][84][85][86][87][88] and used to investigate the incorporation of polyaromatic hydrocarbons, anaesthetic drugs, retinol, and membrane proteins such as gramicidin, principally utilizing electrochemical techniques. This work has also been incorporated into work of Guidelli and co-workers [82,[89][90][91][92][93][94][95][96][97][98][99][100][101] and Rueda et al [85,87,102].…”

Characterization of n-alkanethiol self-assembled monolayers on mercury by impedance spectroscopy and potentiometric measurements

“…These characteristics, along with the very high affinity of mercury toward a variety of organic molecules, make it an ideal substrate for assembling pinholes-free SAMs. Accordingly, condensed films of substances such as fatty acids [14][15][16], alcohols [17][18][19][20], quinolines [21], uracil derivatives [22,23], phospholipids [24][25][26][27][28][29][30][31][32][33][34][35][36][37][38] etc. have been formed on Hg and studied using, in particular, capacity as well as voltammetric measurements.…”