Phosphorescence and ODMR study of the binding interactions of acetylcholine receptor α‐subunit peptides with α‐cobratoxin

Three-dimensional structures of neurotoxins and cardiotoxins

“…This could explain the higher affinity of the neurotoxins compared to acetylcholine. It is also consistent with a study by Trp phosphorescence and optical detection of magnetic resonance (ODMR), which indicated an increased hydrophobic Trp environment in synthetic peptides reproducing the binding-site regions of the AChR, upon binding on a-cobratoxin (45).…”