2021
DOI: 10.1002/jccs.202100475
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Phosphorus‐nitrogen compounds part 59. The syntheses of tetrachloro and tetraamino‐2‐pyridylmethylspiro(N/N)ethylenediaminocyclotriphosphazenes: Structural characterization, bioactivity, and molecular docking studies

Abstract: In this study, primarily, tetrachloro-2-pyridylmethylspiro-N/N-ethylenediaminocyclotriphosphazenes (4 and 5) were prepared from the reactions of equimolar amounts of N-alkyl-N 0 -2-pyridylmethylethylenediamines, [PyCH 2 NH(CH 2 ) 2 NHR (R:CH 3 , 2 and R:C 2 H 5 , 3)], and hexachlorocyclotriphosphazene [(HCCP, trimer), N 3 P 3 Cl 6 (1)]. Compounds 4 and 5 react with secondary amines to yield the fully substituted tetraamino-2-pyridylmethylspiro-N/N-ethylenediaminocyclotriphosphazenes (4a-5c) in dry THF, respect… Show more

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Cited by 9 publications
(2 citation statements)
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“…In this way, a great deal of application and usage fields of and anticancer, antituberculosis, antifungal and antibacterial agents. 19,20 On the other hand, the carbonic anhydrase (CA) superfamily includes metalloenzymes divided into eight genetic families, a-, b-, g-, d-, z-, Z-, yand i-. CAs catalyze the hydrolysis of carbon dioxide (CO 2 ) and water (H 2 O) to bicarbonate (HCO 3 À ) and proton (H + ) in all living organisms.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…In this way, a great deal of application and usage fields of and anticancer, antituberculosis, antifungal and antibacterial agents. 19,20 On the other hand, the carbonic anhydrase (CA) superfamily includes metalloenzymes divided into eight genetic families, a-, b-, g-, d-, z-, Z-, yand i-. CAs catalyze the hydrolysis of carbon dioxide (CO 2 ) and water (H 2 O) to bicarbonate (HCO 3 À ) and proton (H + ) in all living organisms.…”
Section: Introductionmentioning
confidence: 99%
“…as second-order nonlinear optics, 8 biomaterials, 9 organic field effect transistors (OFETs), 10 nanomaterials, 11 fluorescent receptors 12 and chemosensors, 13 ionic liquids, 14 biosensors, 15 protic molten salts, 16 dye-sensitized solar cells, 17 organometallic catalysts 18 and anticancer, antituberculosis, antifungal and antibacterial agents. 19,20…”
Section: Introductionmentioning
confidence: 99%