Abstract:Open tibial fracture surgery was performed on ovariectomized mice to investigate the effect of phosphorylated peptides from Antarctic Krill (PP‐AKP) on osteoporotic fracture healing. Dynamic histological analysis on days 11, 24, and 35 postsurgery showed that PP‐AKP promoted hypertrophy and mineralization of cartilage callus, formation of new bone tissue, and remodeling of boney callus. Biomechanical property tests on day 35 postsurgery demonstrated that PP‐AKP significantly improved callus stiffness. Real‐tim… Show more
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