1947
DOI: 10.1086/physzool.20.2.30151947
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Phosphorylation in the Frog's Egg

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Cited by 45 publications
(7 citation statements)
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“…It is worth mentioning that decreased capacity to keep ATP in the phosphorylated form during anaerobiosis and reduced utilization of glycogen might very well prove to be biochemical abnormalities characteristic of any cell the nucleus of which is severely altered: these very same metabolic troubles have already been found in strongly lethal interspecific frog hybrids (Barth and Jaeger, 1947;Gregg, 1948), as well as in frog eggs fertilized with nitrogen-mustard-treated sperm (unpublished experiments).…”
Section: The Nucleus and The Production Of Coenzymesmentioning
confidence: 83%
See 1 more Smart Citation
“…It is worth mentioning that decreased capacity to keep ATP in the phosphorylated form during anaerobiosis and reduced utilization of glycogen might very well prove to be biochemical abnormalities characteristic of any cell the nucleus of which is severely altered: these very same metabolic troubles have already been found in strongly lethal interspecific frog hybrids (Barth and Jaeger, 1947;Gregg, 1948), as well as in frog eggs fertilized with nitrogen-mustard-treated sperm (unpublished experiments).…”
Section: The Nucleus and The Production Of Coenzymesmentioning
confidence: 83%
“…The amount of phosphagen does, it is true, appear to increase shortly after fertilization, but the time relations do not fit in at all with the reservoir hypothesis (Chambers and Mende, 1953). Moreover both these compounds appear to be freely available to the cell as a whole, as they decrease during anaerobiosis (Barth and Jaeger, 1947;Cleland, 1953). But the postulated store of energy in the reservoir does not get used charge and protein supply and can be upset or reversed experimentally (in Sorghum, Darlington and Thomas, 1941, Proc.…”
Section: The Nature Of the Reservoirmentioning
confidence: 89%
“…Nous avons indiqué, dans l'introduction de ce travail, qu'il nous semblait peu probable que le mercaptoéthanol agisse simplement en produisant une anaérobiose partielle. Les présents dosages d'ATP confirment cette manière de voir : on sait que l'anaérobiose diminue ( assez lentement, il est vrai ) la teneur en ATP des oeufs de Batraciens (Barth et Jaeger, 1947;Brachet, 1955). Or, s'il se produit un changement dans la teneur en ATP des oeufs traités au mercaptoéthanol, il est très faible et il va dans le sens d'une augmentation.…”
Section: Discussionunclassified
“…On voit que, dans ces conditions, le mercaptoéthanol et la mercaptoéthylgluconamide n'exercent qu'un effet inhibiteur modéré vis-à-vis de leurs témoins respectifs (de l'ordre de 25% et 15%, respectivement). Nos résultats, dans le cas du mercaptoéthanol, concordent avec ceux de Mazia (1958a) Malgré les écarts assez considérables d'une expérience à l'autre, on peut tirer quelques conclusions de ces dosages : tout d'abord, comme l'avaient déjà montré Barth et Jaeger (1947), il ne se produit pas de changements importants dans la teneur en ATP au cours du développement chez la grenouille. Il en résulte que les valeurs trouvées pour les deux sortes de témoins (20° et 5°) concordent bien.…”
Section: •3 Comommafion D'oxygèneunclassified
“…Basing upon the techniques of BARTH and JAEGER (1947) and of SCHNE~DER (1945), the extraction and separation of these diffrent P fractions were carried out according to the procedure shown in the scheme (p. 169). A further analysis of acid soluble P was carried out by the method of LEPAGE (1949) with some modifications.…”
Section: Methodsmentioning
confidence: 99%