Phosphorylation of Serine-Rich Protein Encoded by Open Reading Frame 3 of the TT Virus Genome

Genomic characterization of a Brazilian TT Virus isolate closely related to SEN virus-F

“…3). The most conserved region was the C-terminal portion of ORF3 product, a post-translationally phosphorylated serine-rich region that has been suggested to modulate function of host cellular proteins and to play a role in maintaining persistent infection (Asabe et al 2001). SENV-F ORF4 product appeared to be truncated when compared to the corresponding products of SAa-38 and clone 5-A.…”

The Association of Prevalence and Genotypes of Torque Teno Virus (TTV) Among Chronic Hepatitis B and C Patients in Ahvaz, 2012

“…These results differ from the results of this study. This difference may be due to the geographical distribution of TTV, heterogenecity and the variability of the genome (16,17). Another study from India by Asim et al, using 5' UTR primers, reported TTV-DNA was detected in 20 (21.5%) out of 93 samples from patients with chronic hepatitis, including chronic hepatitis B and C patients, hepatitis G patients, and non-A-G hepatitis patients.…”

Investigation of the occurrence of torque tenovirus in malignant and potentially malignant disorders associated with human papillomavirus

“…TTVs were shown to decrease the inflammatory response [Zheng et al, 2007] and may suppress the interferon production and the gene expression related to interferon [Asabe et al, 2001]. Two of these effects (decreased interferon production and the decrease of the inflammatory response) may also act in a paracrine manner even if the TTV does not reside in the epithelial cells.…”