Photo‐Triggered Synthesis of Sulfonamides in a Sustainable SolventviaElectron Donor‐Acceptor Complex

Abstract

A visible-light-triggered synthesis of sulfonamide was developed via an electron donor-acceptor (EDA) complex in the more environmentally friendly green solvent 2-methyltetrahydrofuran (MeTHF). This method offers a novel strategy for synthesizing sulfonamide in high yields at room temperature, without the need of a base, any additional photocatalyst, or transition metals. Simple operation, mild reaction conditions, excellent atom economy, and excellent functional group compatibility are the main advantages of this reaction.

Photo-triggered C-arylation of active-methylene compounds with diazonium salts via an electron donor–acceptor (EDA) complex

“…Given our interest in photoinduced reactions 43,44 and the desirable properties of visible-light-initiated reactions, we focused on this type of reaction. We present a novel coupling method involving the reaction of an aryl radical with an active methylene compound under visible light under mild conditions, without the need for a photocatalyst leading to a biologically active compound.…”

Photoinduced, Metal-Free Hydroacylation of Aromatic Alkynes for Synthesis of α,β-Unsaturated Ketones via C(sp3)–H Functionalization

“…In this methodology, we have incorporated methyl arenes as an acyl radical precursor via C(sp 3 )–H functionalization for the first time. Hence, there has been a rapid increase in interest in using organic dyes as metal-free photocatalysts enabled by photoenergy, which offers excellent prospects for creating ecologically sustainable and effective methods for achieving molecular assembly. , Enlightened by the advancements in sustainable development and ongoing investigation into photoinduced reactions using organic photocatalysts in our laboratory, herein, we have developed a green, effective, gentle, and metal-free protocol for the synthesis of chalcones through photocatalytic hydroacylation of terminal alkynes under mild conditions and ambient air as oxidant (Scheme d).…”