“…Carriers of this secretor phenotype reached the typical interaction time of solubilization quicker than non-secretors. However, the question is if this is clinically relevant as the difference was 5 min and the total time it took to dissolve in mucus was similar [7,8].…”
Section: Solubilization Of Antibiotic In Mucus Layer (Table S5 Part 1)mentioning
After deposition in the airways, the local efficacy of inhaled antibiotics can be reduced by molecules within CF mucus and the alginate layer surrounding P. aeruginosa.
“…Carriers of this secretor phenotype reached the typical interaction time of solubilization quicker than non-secretors. However, the question is if this is clinically relevant as the difference was 5 min and the total time it took to dissolve in mucus was similar [7,8].…”
Section: Solubilization Of Antibiotic In Mucus Layer (Table S5 Part 1)mentioning
After deposition in the airways, the local efficacy of inhaled antibiotics can be reduced by molecules within CF mucus and the alginate layer surrounding P. aeruginosa.
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