Photoactivation of Erythrosine in simulated body fluids

Production of singlet oxygen from photosensitizer erythrosine for facile inactivation of coronavirus on mask

“…As a visible light photosensitizer, erythrosine has conjugated carbon–carbon bonds networks that provide absorption at longer wavelengths ( Bergmann et al, 2021 ). These conjugated networks are susceptible to 1 O 2 oxidation and direct photolysis, which destroys conjugation and eliminates absorbance in the visible spectrum, leading to color fading of the solution (photobleaching) and formation of photooxidation products ( Beltukova et al, 2017 , Kravchenko et al, 2022 ).…”

“…3), a U.S. Food and Drug Administration-approved food dye, as a photosensitizer for photodynamic disinfection. Based on the photobleaching characteristics of erythrosine ( Bergmann et al, 2021 ), the correlation between the inactivation effect of erythrosine against the virus and its color change was investigated, and the complete loss of color caused by photobleaching was taken as the safety indication of complete disinfection. With similar structural features to SARS-CoV-2, transmissible gastroenteritis virus (TGEV) has already been used as a surrogate for SARS-CoV-2 ( Cantero et al, 2022 ).…”