Photoactive nanoparticles capped with macrocycles as platforms and hosts

Li, Zheng; Li, Xi; Yang, Ying‐Wei

doi:10.1016/b978-0-12-814531-9.00006-3

Cited by 2 publications

(3 citation statements)

References 108 publications

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“…The combination of macrocyclic hosts and photoactive inorganic nanomaterials allows for the design of new functional photoactive inorganic-organic hybrid nanomaterials that benefit from the properties of the individual counterparts [1]. Our interest in this communication focuses on photoactive nanohybrids which combine recognition based on host-guest chemistry and the unique photophysical properties of photoactive nanoparticles [2]. Macrocycles, such as crown ether, cyclodextrins, calixarenes, cucurbiturils, and pillarenes, do not only confer hydrophilicity to the resulting nanohybrids, but also preserve their supramolecular recognition capacity for subsequent self-assembly when acting as surface capping agents for photoactive inorganic nanoparticles [2].…”

Section: Introductionmentioning

confidence: 99%

“…Our interest in this communication focuses on photoactive nanohybrids which combine recognition based on host-guest chemistry and the unique photophysical properties of photoactive nanoparticles [2]. Macrocycles, such as crown ether, cyclodextrins, calixarenes, cucurbiturils, and pillarenes, do not only confer hydrophilicity to the resulting nanohybrids, but also preserve their supramolecular recognition capacity for subsequent self-assembly when acting as surface capping agents for photoactive inorganic nanoparticles [2]. Moreover, these nanohybrids could be used as stimuli-responsive smart nanocarriers to deliver a selected encapsulated cargo [3,4].…”

Section: Introductionmentioning

confidence: 99%

“…Cyclodextrins are cyclic oligosaccharides which contain a doughnut-shaped structure (α-, β-, and γ-CD) and have received considerable attention for UCNP post-synthetic surface modification to provide them water-dispersibility while retaining the molecular recognizing capacity of the macrocyclic capping [2,9]. For example, the simple phase transfer of OA-stabilized UCNPs from organic phase to water medium has been conducted with γ-CD and α-CD by forming host-guest complexes with OA [10,11].…”

Section: Introductionmentioning

confidence: 99%

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Initial Biological Assessment of Upconversion Nanohybrids

et al. 2021

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Nanoparticles for medical use should be non-cytotoxic and free of bacterial contamination. Upconversion nanoparticles (UCNPs) coated with cucurbit[7]uril (CB[7]) made by combining UCNPs free of oleic acid, here termed bare UCNPs (UCn), and CB[7], i.e., UC@CB[7] nanohybrids, could be used as photoactive inorganic-organic hybrid scaffolds for biological applications. UCNPs, in general, are not considered to be highly toxic materials, but the release of fluorides and lanthanides upon their dissolution may cause cytotoxicity. To identify potential adverse effects of the nanoparticles, dehydrogenase activity of endothelial cells, exposed to various concentrations of the UCNPs, was determined. Data were verified by measuring lactate dehydrogenase release as the indicator of loss of plasma membrane integrity, which indicates necrotic cell death. This assay, in combination with calcein AM/Ethidium homodimer-1 staining, identified induction of apoptosis as main mode of cell death for both particles. The data showed that the UCNPs are not cytotoxic to endothelial cells, and the samples did not contain endotoxin contamination. Higher cytotoxicity, however, was seen in HeLa and RAW 264.7 cells. This may be explained by differences in lysosome content and particle uptake rate. Internalization of UCn and UC@CB[7] nanohybrids by cells was demonstrated by NIR laser scanning microscopy.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Initial Biological Assessment of Upconversion Nanohybrids

et al. 2021

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The Role of Calix[n]arenes and Pillar[n]arenes in the Design of Silver Nanoparticles: Self-Assembly and Application

Padnya

Gorbachuk

Stoikov

2020

IJMS

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Silver nanoparticles (AgNPs) are an attractive alternative to plasmonic gold nanoparticles. The relative cheapness and redox stability determine the growing interest of researchers in obtaining selective plasmonic and electrochemical (bio)sensors based on silver nanoparticles. The controlled synthesis of metal nanoparticles of a defined morphology is a nontrivial task, important for such fields as biochemistry, catalysis, biosensors and microelectronics. Cyclophanes are well known for their great receptor properties and are of particular interest in the creation of metal nanoparticles due to a variety of cyclophane 3D structures and unique redox abilities. Silver ion-based supramolecular assemblies are attractive due to the possibility of reduction by “soft” reducing agents as well as being accessible precursors for silver nanoparticles of predefined morphology, which are promising for implementation in plasmonic sensors. For this purpose, the chemistry of cyclophanes offers a whole arsenal of approaches: exocyclic ion coordination, association, stabilization of the growth centers of metal nanoparticles, as well as in reduction of silver ions. Thus, this review presents the recent advances in the synthesis and stabilization of Ag (0) nanoparticles based on self-assembly of associates with Ag (I) ions with the participation of bulk platforms of cyclophanes (resorcin[4]arenes, (thia)calix[n]arenes, pillar[n]arenes).

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Photoactive nanoparticles capped with macrocycles as platforms and hosts

Cited by 2 publications

References 108 publications

Initial Biological Assessment of Upconversion Nanohybrids

Initial Biological Assessment of Upconversion Nanohybrids

The Role of Calix[n]arenes and Pillar[n]arenes in the Design of Silver Nanoparticles: Self-Assembly and Application

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