Photoactive Poly-L-Lysine gel with resveratrol-magnesium metal polyphenol network: A promising strategy for preventing tracheal anastomotic complications following surgery

Jia, Yunxuan; Shi, Jingfeng; Ding, Bowen; Zhao, Liang; Xu, Ke; Hu, Chuang; Xu, Weijiao; Zhu, Anshun; Yang, Haitang; Wang, Xiansong; Yao, Feng

doi:10.1016/j.mtbio.2023.100938

Materials Today Bio

2024

DOI: 10.1016/j.mtbio.2023.100938

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Photoactive Poly-L-Lysine gel with resveratrol-magnesium metal polyphenol network: A promising strategy for preventing tracheal anastomotic complications following surgery

Yunxuan Jia,

Jingfeng Shi,

Bowen Ding

et al.

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Adenoid cystic carcinoma: insights from molecular characterization and therapeutic advances

Jia,

Liu,

Yang

et al. 2024

MedComm

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Adenoid cystic carcinoma (ACC) is a malignant tumor primarily originating from the salivary glands, capable of affecting multiple organs. Although ACC typically exhibits slow growth, it is notorious for its propensity for neural invasion, local recurrence, and distant metastasis, making it a particularly challenging cancer to treat. The complexity of ACC's histological and molecular features poses significant challenges to current treatment modalities, which often show limited effectiveness. Recent advancements in single‐cell RNA‐sequencing (scRNA‐seq) have begun to unravel unprecedented insights into the heterogeneity and subpopulation diversity within ACC, revealing distinct cellular phenotypes and origins. This review delves into the intricate pathological and molecular characteristics of ACC, focusing on recent therapeutic advancements. We particularly emphasize the insights gained from scRNA‐seq studies that shed light on the cellular landscape of ACC, underscoring its heterogeneity and pathobiology. Moreover, by integrating analyses from public databases, this review proposes novel perspectives for advancing treatment strategies in ACC. This review contributes to the academic understanding of ACC by proposing novel therapeutic approaches informed by cutting‐edge molecular insights, paving the way for more effective, personalized therapeutic approaches for this challenging malignancy.

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Adenoid cystic carcinoma: insights from molecular characterization and therapeutic advances

Jia,

Liu,

Yang

et al. 2024

MedComm

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Resveratrol nanoparticles coated by metal-polyphenols supramolecular enhance antioxidant activity and long-term stability of dietary gel

Chai,

Zhou,

Zhang

et al. 2025

Food Chemistry

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Photoactive Poly-L-Lysine gel with resveratrol-magnesium metal polyphenol network: A promising strategy for preventing tracheal anastomotic complications following surgery

Cited by 2 publications

References 50 publications

Adenoid cystic carcinoma: insights from molecular characterization and therapeutic advances

Adenoid cystic carcinoma: insights from molecular characterization and therapeutic advances

Resveratrol nanoparticles coated by metal-polyphenols supramolecular enhance antioxidant activity and long-term stability of dietary gel

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