2023
DOI: 10.1021/acs.chemrev.2c00767
|View full text |Cite
|
Sign up to set email alerts
|

Photobiocatalytic Strategies for Organic Synthesis

Abstract: Biocatalysis has revolutionized chemical synthesis, providing sustainable methods for preparing various organic molecules. In enzyme-mediated organic synthesis, most reactions involve molecules operating from their ground states. Over the past 25 years, there has been an increased interest in enzymatic processes that utilize electronically excited states accessed through photoexcitation. These photobiocatalytic processes involve a diverse array of reaction mechanisms that are complementary to one another. This… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

1
40
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
7
1

Relationship

1
7

Authors

Journals

citations
Cited by 116 publications
(41 citation statements)
references
References 233 publications
1
40
0
Order By: Relevance
“…Biocatalytic photosynthesis merging the biocatalysis and photocatalysis has become of great interest in the field of synthetic chemistry. [87][88][89][90][91] In 2019, the Hyster group exploited this strategy to realize the enantioselective reduction of ketones through a combination of an ene-reductase and a ruthenium photocatalyst (Scheme 24). [92] This transformation is found to be compatible with diaryl and aryl alkyl ketones, affording chiral alcohols in moderate to good yields with moderate enantioselectivities.…”
Section: Biocatalyst Combing Photoredox Catalystmentioning
confidence: 99%
“…Biocatalytic photosynthesis merging the biocatalysis and photocatalysis has become of great interest in the field of synthetic chemistry. [87][88][89][90][91] In 2019, the Hyster group exploited this strategy to realize the enantioselective reduction of ketones through a combination of an ene-reductase and a ruthenium photocatalyst (Scheme 24). [92] This transformation is found to be compatible with diaryl and aryl alkyl ketones, affording chiral alcohols in moderate to good yields with moderate enantioselectivities.…”
Section: Biocatalyst Combing Photoredox Catalystmentioning
confidence: 99%
“…The new frontier for the assembling of molecular frameworks entails the utilization of photobiocatalytic strategies. [79] The first asymmetric photoenzymatic catalyzed procedure for the reaction of nitroalkanes with α-chloroamides has been realized very recently using a flavin-dependent 'ene'-reductase (ERED) jointly with cyan LED irradiation. [80] The alkylation was successfully carried out but the nitro group was contextually eliminated as nitrite anion leading to the formation of enantioenriched alkylated amides.…”
Section: Photoenzymatic Catalyzed Processesmentioning
confidence: 99%
“…[6,7] Solar fuel synthesis using microbial systems, [8][9][10] in particular, is a vital emerging approach to environmentally sustainable solar energy conversion [11][12][13] due to its high selectivity, [14] feasibility, [15] and durability. [16,17] Efficient lab-scale microbial fuel production, [18][19][20] including microbial solar hydrogen (H 2 ) production, [21,22] has been achieved by recent research efforts such as advanced genetic engineering [23][24][25] and incorporation of semiconductor biohybrids. [26,27] However, the practical use of conventional microbial fuel production systems has been impeded, primarily by system-level design challenges such as ineffective supply of reactants and capture of products [28,29] as well as by the requirement of electrodes [30,31] and scale-up issues.…”
Section: Introductionmentioning
confidence: 99%