Photocatalytic Aerobic Oxysulfonylation of Alkynes to Access β‐Keto Sulfones Catalyzed by OVs‐N‐Nb₂O₅

Abstract

Herein, we report a novel heterogeneous photocatalyst for radical-mediated oxidative oxysulfonylation of alkynes to β-keto sulfones under environmentally benign conditions. The oxygen vacancy-rich semiconductor Nb 2 O 5 (labeled as OVs-N-Nb 2 O 5 ) could efficiently catalyze a wide range of alkynes, especially for those bearing electron-deficient substituents or internal alkynes, to their corresponding β-keto sulfones in good to high yields with good tolerance of diverse functional groups under visible-light illumination. The late-stage modification of steroidal compounds and synthesis of bioactive molecules were also achieved via this procedure, highlighting its potential for practical applications. Meanwhile, the photocatalyst OVs-N-Nb 2 O 5 showed outstanding catalytic stability for successive recycles without appreciable loss in activity and selectivity. The critical role of oxygen vacancies on improving reaction activity and selectivity was clearly disclosed via control experiments and theoretical calculation.

Immobilizing Triphenylamine with Photoredox Inert Sr2+ Forming Sr‐MOF with Controlled Electron Migration for Photocatalytic Oxidation of Thiols to Disulfides

“…[ 8‐10 ] Over the past decades, numerous methods have been reported for this process, [ 11‐16 ] among which the aerobic photocatalytic method, economical and eco‐friendly, is considered as the most promising. [ 17‐22 ] Compared with the traditional inorganic semiconductors or noble metal‐containing complex, the organic dyes show enhanced stability, easy modifications and reduced costs, thus garnering much attentions as a photocatalyst. [ 23‐26 ] Triphenylamine and its derivatives (TPAs) are one of the common organic dyes, possessing outstanding electron‐donating ability, superb hole transport performance and low ionization potential, [ 27‐30 ] exhibiting immense application potentials in the photocatalytic oxidative synthesis of disulfides.…”

Regulation of Photogenerated Redox Species through High Crystallinity Carbon Nitride for Improved C−S Coupling Reactions

“…The authors have cited additional references within the Supporting Information (Ref. [30][31][32][33][34][35][36][37][38][39][40][41][42][43]).…”