Photocatalytic effects of reactively sputtered N-doped anatase upon irradiation at UV-A and UV-A/VIS threshold wavelengths

Antimicrobial dental implant functionalization strategies —A systematic review

“…UVA light-induced photofunctionalization of TiO2 surfaces have been investigated in vitro and in in vivo rat models but have not been tested in humans due to the possible cell damage in host tissues. Its applicability is currently restricted to light-accessible dental implant surfaces 168,169) .…”

Antibacterial photocatalytic activity of different crystalline TiO2 phases in oral multispecies biofilm

“…Additionally, the findings and methodology developed on this study can help to change the bandgap of TiO 2 and enable its activation by a visible light in the future [13], as long as a minimum of 7% photocatalytic degradation activity is achieved, as this seems to be our threshold percentage to achieve significant antibacterial effect. In this context, we hope that this percentage can soon be achieved with longer wavelengths, in order to still generate photocatalytic attack of biofilms, but also enhance the clinical acceptance of this treatment, extending its use for intra oral areas.…”

“…For this reason, in order to reduce bacterial colonization to dental implants and their components, some photocatalytic compounds, such as titanium dioxide (TiO 2 ), have been incorporated to their surfaces [9][10][11][12][13]. When photocatalyzed TiO 2 produces reactive oxygen species (ROS) [14] that promotes the degradation of bacterial membranes, therefore presenting an antibacterial effect [15].…”

“…Several methods are used for TiO 2 deposition on biomaterials such as sol-gel [24,25], spin-coating [12,26], anodization [9,10,27], atomic layer deposition [28] and magnetron sputtering [11,13,[29][30][31] . Magnetron sputtering is a extensively used method as it produces films with greater adhesion, hardness and hydrophilicity [19,30,32,33], and it is also able to generate isolated phases of anatase and rutile [34].…”