Photochemical degradation kinetics and mechanisms of norfloxacin and oxytetracycline

Xue, Honghai; Li, Ming; Liu, Binshuo; Meng, Qingling

doi:10.1007/s11356-020-11181-5

Cited by 14 publications

(7 citation statements)

References 25 publications

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“…There are various reports showing the photodegradation of several medicines, such as non-steroidal anti-inflammatory drugs (NSAIDs), calcium channel blockers, antiepilepsy drugs, antibiotic drugs and beta blockers [1][2][3][4][5][6][7]. These reports suggest that it is important to consider the photostability of the medicine in the case that it might be photo-irradiated.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Photodegradation of Crushed- and Suspended Pranoprofen Tablets

et al. 2021

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Herein, we evaluate the photostability of pranoprofen (PP) tablets (NIFLAN ® 75 mg), its powdered and suspended forms. PP is a member of the 2-arylpropionic acid family of NSAIDs. The content of the active compound was monitored by high-performance liquid chromatography (HPLC) using an ODS column with ultraviolet light (UV) detector. The residual amount of PP in the powder was 86.5%, which was comparable to that of in the suspension (85.4%) after UV irradiation for 24 hr. Further UV irradiation (total irradiation time of 7 days) resulted in the significant photodegradation of PP in the suspension (residual amount: 55.5%), compared to that of 1 day irradiation. However, the residual amount of PP in the powder was 78.6% after 7 days irradiation as the same to that of 1 day irradiation. To identify the chemical structure of five photoproducts generated from the UV-irradiated PP dosage forms, electrospray ionization liquid chromatography mass spectrometry (ESI-LC/MS/MS) analysis was performed. From these results, photodegradation of PP was observed through changing dosage forms. This is the first report evaluating the generation of PP photoproducts induced by the UV irradiation in the formulation.

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Section: Introductionmentioning

confidence: 99%

Evaluation of the Photodegradation of Crushed- and Suspended Pranoprofen Tablets

et al. 2021

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“…The photodegradation mechanism of those pollutants has been well-studied in previous work. For the photodegradation of NFX, hydroxylation and defluorination are the main processes. , For both SFD and SMZ, both excited molecules and reactive oxygen species were involved in the photodegradation process. − The initial concentration of each pollutant in the solution was 5 mg/L. The vial was filled with the micropollutant solution and placed under the simulated solar light (1 sun, SS200AAA Solar Simulation Systems, Photo Emission Tech) for 4 h. All samples after the light treatment were analyzed with UV–vis spectrum to quantify the concentration of the degraded compound for the calculation of η.…”

Section: Methodsmentioning

confidence: 99%

“…For the photodegradation of NFX, hydroxylation and defluorination are the main processes. 44,45 For both SFD and SMZ, both excited molecules and reactive oxygen species were involved in the photodegradation process. 46−48 The initial concentration of each pollutant in the solution was 5 mg/L.…”

Section: ■ Experimental Sectionmentioning

confidence: 99%

Surface Microlenses for Much More Efficient Photodegradation in Water Treatment

Meng

et al. 2022

ACS EST Water

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The global need for clean water requires sustainable technology for purifying contaminated water. Highly efficient solar-driven photodegradation is a sustainable strategy for wastewater treatment. In this work, we demonstrate that the photodegradation efficiency of micropollutants in water can be improved by ∼2–24 times by leveraging polymeric microlenses (MLs). These microlenses (MLs) are fabricated from the in situ polymerization of surface nanodroplets. We found that photodegradation efficiency (η) in water correlates approximately linearly with the sum of the intensity from all focal points of MLs, although no difference in the photodegradation pathway is detected from the chemical analysis of the byproducts. With the same overall power over a given surface area, η is doubled by using ordered ML arrays, compared to heterogeneous MLs on an unpatterned substrate. A higher η from ML arrays may be attributed to a coupled effect from the focal points on the same plane that creates high local concentrations of active species to further speed up the rate of photodegradation. As a proof-of-concept for MLs-enhanced water treatment, MLs were formed on the inner wall of glass bottles that were used as containers for water to be treated. Three representative micropollutants (norfloxacin, sulfadiazine, and sulfamethoxazole) in the bottles functionalized by MLs were photodegraded by 30%–170% faster than in normal bottles. Our findings suggest that the MLs-enhanced photodegradation may lead to a highly efficient solar water purification approach without a large-sized solar collector. Such an approach may be particularly suitable for portable transparent bottles in remote regions.

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“…Among the various strategies developed for environmental remediation, the photocatalytic technique is one of the most promising pathways for the removal of antibiotic contaminants due to its clean, economic, and ecofriendly features. [5][6][7][8][9][10][11] At present, many types of semiconductor photocatalysts have been developed for the photocatalytic degradation of NOR. For instance, Zhao et al reported a kind of N-TiO 2 / graphene layered material that achieved about a 50% degradation of NOR within 160 min under the irradiation of an ultraviolet lamp.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of novel AgI/BiOI nanocomposites and their high-efficiency visible-light-driven photocatalytic degradation performance for norfloxacin

Liu,

Zhong,

Feng

et al. 2024

New J. Chem.

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Photochemical degradation kinetics and mechanisms of norfloxacin and oxytetracycline

Cited by 14 publications

References 25 publications

Evaluation of the Photodegradation of Crushed- and Suspended Pranoprofen Tablets

Evaluation of the Photodegradation of Crushed- and Suspended Pranoprofen Tablets

Surface Microlenses for Much More Efficient Photodegradation in Water Treatment

Synthesis of novel AgI/BiOI nanocomposites and their high-efficiency visible-light-driven photocatalytic degradation performance for norfloxacin

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