Photochemotherapy of oral lichen planus

Lundquist, Gunilla; Forsgren, Hanz; Gajecki, Maria; Emtestam, Lennart

doi:10.1016/s1079-2104(05)80094-0

Cited by 93 publications

(43 citation statements)

References 25 publications

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“…This treatment may be useful for severe forms of erosive OLP that do not respond to conventional treatment (51, 52). On the other hand, classical PUVA therapy seems to have many side‐effects such as nausea, dizziness, eye symptoms, paresthesia, and headache (53). Moreover, one matter for concern is that long‐wave ultraviolet‐A (PUVA) therapy has been shown to have oncogenic potential (54).…”

Section: Discussionmentioning

confidence: 99%

Clinical evaluation in treatment of oral lichen planus with topical fluocinolone acetonide: a 2‐year follow‐up

Thongprasom

Luengvisut

Wongwatanakij

et al. 2003

J Oral Pathology Medicine

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Section: Discussionmentioning

confidence: 99%

Clinical evaluation in treatment of oral lichen planus with topical fluocinolone acetonide: a 2‐year follow‐up

Thongprasom

Luengvisut

Wongwatanakij

et al. 2003

J Oral Pathology Medicine

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“…It has been successfully used in the treatment of severe cases of OLP. [27] Two major disadvantages of PUVA therapy include the adverse effects of nausea and dizziness secondary to psoralen and 24-hour photosensitivity when this medicine is taken orally. Also, dosimetry can be difficult within the complicated geometry of the mouth, because PUVA is usually administered on skin over large, open surfaces.…”

Section: Non-pharmacological Modalitiesmentioning

confidence: 99%

Oral lichen planus: An update on pathogenesis and treatment

Lavanya

Jayanthi

Rao

et al. 2011

J Oral Maxillofac Pathol

269

215

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Oral lichen planus (OLP) is a chronic inflammatory disease that affects the mucus membrane of the oral cavity. It is a T-cell mediated autoimmune disease in which the cytotoxic CD8+ T cells trigger apoptosis of the basal cells of the oral epithelium. Several antigen-specific and nonspecific inflammatory mechanisms have been put forward to explain the accumulation and homing of CD8+ T cells subepithelially and the subsequent keratinocyte apoptosis. A wide spectrum of treatment modalities is available, from topical corticosteroids to laser ablation of the lesion. In this review, we discuss the various concepts in the pathogenesis and current treatment modalities of OLP.

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“…Systemic etretinate, dapsone, or photochemotherapy have also been reported to be effective in severe resistant cases. [1718]…”

Section: Discussionmentioning

confidence: 99%

Chronic desquamative gingivitis in siblings: A report of two cases

Vijayakar

Shah

Desai

et al. 2014

J Indian Soc Periodontol

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Desquamative gingivitis is a gingival response associated with a variety of clinical conditions and characterized by intense erythema, desquamation and ulceration of free and attached gingiva. A variety of diseases such as lichen planus, pemphigus, pemphigoid, dermatitis herpetiformis, linear IgA disease, lupus erythematosus, erythema multiformae manifest clinically as desquamative gingivitis. Of all the disease entities, Lichen Planus is a relatively common disorder affecting the skin and mucous membrane. Very often it has oral manifestations. These lesions of oral lichen planus (OLP) have myriad but distinct morphology. As they mimic other mucocutaneous disorders with regard to clinical appearance, many lesions of oral lichen planus go undiagnosed or are wrongly diagnosed. Reported here are two cases of desquamative gingivitis. One of these was diagnosed as erosive lichen planus based on the symptoms, clinical findings, histologic, and immunofluorescent examination. Further management was done in consultation with a dermatologist.

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Photochemotherapy of oral lichen planus

Cited by 93 publications

References 25 publications

Clinical evaluation in treatment of oral lichen planus with topical fluocinolone acetonide: a 2‐year follow‐up

Clinical evaluation in treatment of oral lichen planus with topical fluocinolone acetonide: a 2‐year follow‐up

Oral lichen planus: An update on pathogenesis and treatment

Chronic desquamative gingivitis in siblings: A report of two cases

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