2023
DOI: 10.1016/j.matdes.2023.111915
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Photocurable hydrogel-elastomer hybrids as an adhesive patch for meniscus repair

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Cited by 7 publications
(5 citation statements)
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“…Among various types of meniscus tears, radial tear in white–white zone is the most challenging one due to the lack of blood flow in the region 4 , 45 . The fabricated S-PIL10 was typically applied to radial tear and the entire experimental procedures including creating meniscus tear model and in-situ adhesive operation were shown in Fig.…”
Section: Resultsmentioning
confidence: 99%
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“…Among various types of meniscus tears, radial tear in white–white zone is the most challenging one due to the lack of blood flow in the region 4 , 45 . The fabricated S-PIL10 was typically applied to radial tear and the entire experimental procedures including creating meniscus tear model and in-situ adhesive operation were shown in Fig.…”
Section: Resultsmentioning
confidence: 99%
“…In the second part, apart from the excellent mechanical properties, the qualified hydrogel adhesive should promote the repair and regeneration of the adhered torn meniscus in consideration of the actual in vivo condition due to the self-unhealable characteristic in white–white zone. As reported, Wei designed a hydrogel-elastomer hybrid as adhesive patch to promote the meniscus repair in red–red zone, but the repair in white–white zone was mainly with the aid of growth factors or cytokines 39 , 45 . Hence, the growth factor TGF-β1 was loaded into the meniscus adhesive S-PIL10 to promote effective healing in the avascular region.…”
Section: Discussionmentioning
confidence: 99%
“…Zhao et al have developed double cross-linked biomimetic HA-based hydrogels with thermo-stimulated self-contraction and tissue adhesiveness for accelerating postwound closure and wound healing . However, HA cannot be gelatinized itself . Previous researches reported that o -nitrobenzene (NB) was modified onto an HA molecule chain to obtain a phototriggered macromolecule HANB (HN); furthermore, NB modification made it possible for hydrogel to connect to the skin tissue through a Schiff-base reaction …”
Section: Introductionmentioning
confidence: 99%
“…23 However, HA cannot be gelatinized itself. 24 Previous researches reported that onitrobenzene (NB) was modified onto an HA molecule chain to obtain a phototriggered macromolecule HANB (HN); 25 The extracellular matrix (ECM) plays a crucial role in constructing a physical extracellular environment, signal transduction, and cell migration. 27 Recently, abundant research for the application of the ECM in the field of injured tissue repair has been published.…”
Section: Introductionmentioning
confidence: 99%
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