Photodynamic Therapy During Supportive Periodontal Care: Clinical, Microbiologic, Immunoinflammatory, and Patient‐Centered Performance in a Split‐Mouth Randomized Clinical Trial

Abstract

PDT as an exclusive therapy may be considered a non-invasive alternative for treating residual pockets, offering advantages in the modulation of cytokines.

Microbiological outcomes from different periodontal maintenance interventions: a systematic review

“…Among these studies, only four reported the microbiological outcomes by numeric results on tables. 25,26,27,28 Real-time PCR: Kolbe et al 27 showed a non-significant trend to decrease the quantities (amounts: log 10 ± SEM) of P. gingivalis (1.6 ± 1.4 to 1.0 ± 1.4) and T. forsythia (4.9 ± 3.6 to 4.7 ± 3.8) from PMP baseline to 6 months, respectively, and stability for A. actinomycetemcomitans (2.7 ± 3.1 to 2.7 ± 2.5). There were no differences over time in the percentage of sites harboring T. forsythia and A. actinomycetemcomitans, whereas a significant decrease in the frequency of P. gingivalis was observed.…”

Is Photodynamic Therapy an Effective Treatment for Periodontal and Peri-Implant Infections?

“…[49][50][51] Three out of the 8 studies have also evaluated the changes in terms of inflammatory markers. 47,50,52 Two studies have revealed statistically significantly higher reductions in the investigated inflammatory markers following the use of PDT, 47,50 while one study detected no differences 52 (Table 3). …”

“…44,45 An additional improvement for the reduction of BOP was reported in 5 out of the 8 studies. [44][45][46][47][48] While three studies have found a statistically significant effect of the additional use of PDT on the reduction of periodontal pathogens, [46][47][48] three other studies have failed to reveal statistically significant differences between the treatment groups. [49][50][51] Three out of the 8 studies have also evaluated the changes in terms of inflammatory markers.…”

Application of Antimicrobial Photodynamic Therapy in Dental Treatments

“…Kolbe et al 33) 2014 CP (22) residual pockets during SPT split-mouth a-PDT (22) Diode laser (660 nm, 60 mW) + MB (10 mg/ml), 1 min 6 months • There was no significant difference in improvement of PD and CAL among three group.…”