Photodynamic therapy for obstructing esophageal cancer: Light dosimetry and randomized comparison with Nd: YAG laser therapy

Heier, S.K.; Rothman, K.; Heier, Lawrence M.; Rosenthal, William S.

doi:10.1016/0016-5085(95)90269-4

Cited by 132 publications

(61 citation statements)

References 32 publications

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“…Meta-analysis was not possible due to heterogeneity between the trials. All trials reported morbidity results, seven reported on mortality [113][114][115][116][117][118][119] and four reported on QoL outcomes. [115][116][117][118] Only two of the studies reported resource use, both in terms of days of hospitalisation.…”

Section: Results Of Effectiveness (Palliative Intent)mentioning

confidence: 99%

“…Heier et al 114 found that patients receiving PDT were judged to have significantly greater improvements in dietary performance and Karnofsky performance status. Lightdale et al 112 did not report on this outcome.…”

Section: Quality Of Lifementioning

confidence: 99%

“…[107][108][109][110][111][112][113][114][115][116][117][118][119] Three studies were available only as abstracts, 107,110,111 the rest were published as full papers. In a small number of trials, the presented data did not appear to entirely support the authors' conclusions; this has been indicated in the data extraction tables.…”

Section: Study Characteristicsmentioning

confidence: 99%

See 2 more Smart Citations

A systematic review of photodynamic therapy in the treatment of pre-cancerous skin conditions, Barrett’s oesophagus and cancers of the biliary tract, brain, head and neck, lung, oesophagus and skin

Fayter

Corbett²,

Heirs³

et al. 2010

Health Technol Assess

126

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How to obtain copies of this and other HTA programme reports An electronic version of this title, in Adobe Acrobat format, is available for downloading free of charge for personal use from the HTA website (www.hta.ac.uk). A fully searchable DVD is also available (see below).Printed copies of HTA journal series issues cost £20 each (post and packing free in the UK) to both public and private sector purchasers from our despatch agents.Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per issue and for the rest of the world £3 per issue. How to order:-fax (with credit card details) -post (with credit card details or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you to either print out your order or download a blank order form. Contact details are as follows:Synergie UK (HTA Department) Digital House, The Loddon Centre Wade Road Basingstoke Hants RG24 8QW Email: orders@hta.ac.uk Tel: 0845 812 4000 -ask for 'HTA Payment Services' (out-of-hours answer-phone service) Fax: 0845 812 4001 -put 'HTA Order' on the fax header Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to University of Southampton and drawn on a bank with a UK address. Paying by credit cardYou can order using your credit card by phone, fax or post. SubscriptionsNHS libraries can subscribe free of charge. Public libraries can subscribe at a reduced cost of £100 for each volume (normally comprising 40-50 titles). The commercial subscription rate is £400 per volume (addresses within the UK) and £600 per volume (addresses outside the UK). Please see our website for details. Subscriptions can be purchased only for the current or forthcoming volume. How do I get a copy of HTA on DVD?Please use the form on the HTA website (www.hta.ac.uk/htacd/index.shtml). HTA on DVD is currently free of charge worldwide.The website also provides information about the HTA programme and lists the membership of the various committees. HTA NIHR Health Technology Assessment programmeT he Health Technology Assessment (HTA) programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care. The research findings from the HTA programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a key component of the 'National Knowledge Service'. The HTA programme is needs led in that it fills gaps in the evidence needed by the NHS. There are three routes to the start of project...

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Section: Results Of Effectiveness (Palliative Intent)mentioning

confidence: 99%

Section: Quality Of Lifementioning

confidence: 99%

See 1 more Smart Citation

A systematic review of photodynamic therapy in the treatment of pre-cancerous skin conditions, Barrett’s oesophagus and cancers of the biliary tract, brain, head and neck, lung, oesophagus and skin

Fayter

Corbett²,

Heirs³

et al. 2010

Health Technol Assess

126

View full text Add to dashboard Cite

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“…13 Recently, there has been renewed interest in PDT for palliation of advanced oesophageal cancers, perhaps partly as a way of getting some application of PDT approved by the Food and Drugs Administration (FDA) in the USA. '6 17 The most comprehensive report is a phase III, randomised, multicentre study comparing PDT using Photofrin to Nd:YAG laser therapy in 236 patients with advanced malignant dysphagia from Lightdale et al '6 The response rates, median survival times (PDT: 123 days; Nd:YAG: 140 days), time to palliation failure (PDT: 34 days; Nd:YAG: 42 days) and dysphagia scores were similar for both groups, although the authors admit that their response rates in the Nd:YAG laser group (48% at one week and 29% at one month) are way below the figures of 65-80% in most other studies. They reported fewer treatment endoscopies with PDT, but including the debridement endoscopies required after each PDT treatment, the total number of procedures was similar for both.…”

Section: Leading Articlementioning

confidence: 99%

Photodynamic therapy in gastroenterology.

Bown¹,

Millson²

1997

Gut

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“…13,[16][17][18][19] This chemical, porfimer sodium (Photofrin II, Quadra Logic Technologies, Vancouver, British Columbia), is given intravenously in a dose of 2 mg/kg of body weight. After approximately 48 hours, the area of cancer is exposed to a red light with a wavelength of 630 nm provided by a continuous-wave argon-pumped dye laser via a quartz fiber passed through a standard videoendoscope.…”

Section: Photodynamic Therapymentioning

confidence: 99%

Palliation of Dysphagia of Esophageal Cancer by Endoscopic Lumen Restoration Techniques

1999

Cancer Control

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Photodynamic therapy for obstructing esophageal cancer: Light dosimetry and randomized comparison with Nd: YAG laser therapy

Cited by 132 publications

References 32 publications

A systematic review of photodynamic therapy in the treatment of pre-cancerous skin conditions, Barrett’s oesophagus and cancers of the biliary tract, brain, head and neck, lung, oesophagus and skin

A systematic review of photodynamic therapy in the treatment of pre-cancerous skin conditions, Barrett’s oesophagus and cancers of the biliary tract, brain, head and neck, lung, oesophagus and skin

Photodynamic therapy in gastroenterology.

Palliation of Dysphagia of Esophageal Cancer by Endoscopic Lumen Restoration Techniques

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