Photodynamic therapy for tracheobronchial cancer

Jheon, Sanghoon; Lee, J.M.; Kim, J.-K.; Kim, K.-H.; Seo, Sangmin

doi:10.1016/j.pdpdt.2011.03.176

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2020

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“…PDT currently occupies an increasingly important place in clinical medicine. Its most promising application is the treatment of small and superficial tumors, e.g., some types of skin, neck, stomach [64], lung [65][66][67], bronchial [68] or oral cancer [69], esophagus [70,71], bladder [71,72], brain [73], prostate and pleura [74] tumors, breast [75] but also skin disease [76], atherosclerosis, and viral diseases therapy [77], including AIDS [78].…”

Section: Pdt Applicationsmentioning

confidence: 99%

Biophysical Characterization and Anticancer Activities of Photosensitive Phytoanthraquinones Represented by Hypericin and Its Model Compounds

2020

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Photosensitive compounds found in herbs have been reported in recent years as having a variety of interesting medicinal and biological activities. In this review, we focus on photosensitizers such as hypericin and its model compounds emodin, quinizarin, and danthron, which have antiviral, antifungal, antineoplastic, and antitumor effects. They can be utilized as potential agents in photodynamic therapy, especially in photodynamic therapy (PDT) for cancer. We aimed to give a comprehensive summary of the physical and chemical properties of these interesting molecules, emphasizing their mechanism of action in relation to their different interactions with biomacromolecules, specifically with DNA.

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