Photodynamic Therapy in the Management of Neoplasms of the Perianal Skin

Petrelli, Nicholas J.; Cebollero, Jose Antonio; Rodrı́guez-Bigas, Miguel A.; Mang, Thomas S.

doi:10.1001/archsurg.1992.01420120070013

Cited by 44 publications

(18 citation statements)

References 17 publications

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“…Other treatments include cryosurgery, curettage and electro cautery, excisional surgery, glans resurfacing, micrographic surgery, laser, and topical or syst emic phot odynamic therapy [2, 177,271,[283][284][285][286][287][288][289][290][291][292]. Topical immunomodulators and antivirals such as imiquimod and cidofovir show promise [293][294][295][296][297][298][299][300].…”

Section: Managementmentioning

confidence: 99%

Management of penile dermatoses

Bunker¹

2006

Expert Review of Dermatology

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KEYWORDS:Bowen's disease of the penis, Bowen oid papulosis, circumcision, dysesthesia s y ndrom es, dy sf unct ional f oreskin, erosive lichen planus, erythroplasia of Queyrat, lichen sclerosus, male d ys pare unia, nons peci fic b a l a n o p o st h i t i s, s q u a m o u s carcinoma, Zoon's balanitis M al e g en i t al de r m at ol o gy h a s b een a n eg l ec te d f i el d . M e n w i th ge n i ta l s k i n p ro b l em s ca n p re s en t t o d o ct or s (e .g ., i n u ro l og y or g e n i to u r i n a r y m ed i c i n e) w h o ar e n ot t r ai n e d or experienced in their diagnosis and management. The pathogenesis, epidemiology, n a tu r a l h i s t or y an d p r og n os i s o f m a n y m a l e g en i t al de r m at os e s -Z oo n 's b al an i t i s , er os i v e lichen planus, lichen sclerosus, nonspecific balanoposthitis, dysesthesia syndromes and ca r ci n o m a in situ -are ill-understood and treatment is not eviden ce-based. Althou gh penis cancer is rare, it should be preventable or diagnosable at an early stage, thus reducin g morbidity and mortality. Th e guiding ideology behind diagnosi s and management is to exclude sexually transmitted disease, minimize or abolish sexual and urinary dysfunction and the risk of penis cancer, and to preserve the foreskin if possible. However, much dermatological disease of the male organ can be attributed to the causes or consequences of preputial dysfunction. T h er e i s w i d e n or m al va r i at i on i n th e a n a to my o f t h e pe n i s a n d i ts r e l at i on s h i p t o th e p r ep u ce , pe rh ap s r ef l ect i n g s u s ce pt i b i l i ty to m i n o r em b r y ol o g i ca l a n om a l y. T h e for es k i n i s a de l i c at e, b u sy ti s s u e, i n cl o se c on t ac t w i thu r i n e and exposed to sexual secretions and detergents. These congenital and acquired factors can conspire to produce a dysfu nctional foreskin, often clinically expressed as male sexual dysfunction in the form of male dyspareunia.Expert Rev. Dermatol. 1(2), 24 1-26 0 (2006 )

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Section: Managementmentioning

confidence: 99%

Management of penile dermatoses

Bunker¹

2006

Expert Review of Dermatology

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“…A pair of publications reported the potential sphincter sparing and excellent cosmetic outcome possible for a small group of five patients who failed local excision of in situ squamous cell or Paget's disease of the peri-anal region [13,14]. All patients failed wide local excision and more radical surgery was planned, which may have required colostomy.…”

Section: Discussionmentioning

confidence: 99%

Photodynamic therapy for anal cancer

Allison¹,

Sheng

Cuenca

et al. 2010

Photodiagnosis and Photodynamic Therapy

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“…Photodynamic therapy has also been suggested; however, studies are limited. 28,29 Targeted destruction and follow-up is a more aggressive approach to identifiable lesions. Wide local excision (WLE) has been employed for discrete lesions, with the extent of resection based on preoperative mapping as first described by Strauss and Fazio 30 in 1979, although this in not routinely necessary.…”

Section: Anal Intraepithelial Neoplasia or Squamous Intraepithelial Lmentioning

confidence: 99%

Anal Neoplasms

Garrett

Kalady

2010

Surgical Clinics of North America

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A variety of lesions comprise tumors of the anal canal, with carcinoma in situ and epidermoid cancers being the most common. Less common anal neoplasms include adenocarcinoma, melanoma, gastrointestinal stromal cell tumors, neuroendocrine tumors, and Buschke-Lowenstein tumors. Treatment strategies are based on anatomic location and histopathology. In this article different tumors and management of each, including a brief review of local excision for rectal cancer, are discussed in turn.

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Photodynamic Therapy in the Management of Neoplasms of the Perianal Skin

Cited by 44 publications

References 17 publications

Management of penile dermatoses

Management of penile dermatoses

Photodynamic therapy for anal cancer

Anal Neoplasms

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