Photoinduced arylation or alkylation of 1,2,4-triazine-3,5(2H,4H)-diones with hydrazines

Abstract

An innovative and eco-friendly method has been developed for synthesizing 6-arylated or 6-alkylated 1,2,4-triazine-3,5(2H,4H)-diones, utilizing a photoinduced cross-dehydrogenative coupling reaction with hydrazines.

Photocatalyzed Acylation of Azauracil Derivatives with Aldehydes

“…The emerging field of photocatalysis has revolutionized the efficient formation of chemical bonds using clean solar energy . Particularly noteworthy is the investigation of photocatalytic C–H bond functionalization for the modification of azauracil and its derivatives, attracting global attention from researchers. , Under mild conditions, these photocatalytic reactions for C–H functionalization demonstrate successful alkylation and arylation of azauracil and its derivatives. Nonetheless, effective synthetic approaches for the acylation reactions of azauracil derivatives remain elusive.…”