Photoluminescence Enhancement of Poly(3-methylthiophene) Nanowires upon Length Variable DNA Hybridization

Abstract

Abstract:The use of low-dimensional inorganic or organic nanomaterials has advantages for DNA and protein recognition due to their sensitivity, accuracy, and physical size matching. In this research, poly(3-methylthiophene) (P3MT) nanowires (NWs) are electrochemically prepared with dopant followed by functionalization with probe DNA (pDNA) sequence through electrostatic interaction. Various lengths of pDNA sequences (10-, 20-and 30-mer) are conjugated to the P3MT NWs respectively followed with hybridization with their complementary target DNA (tDNA) sequences. The nanoscale photoluminescence (PL) properties of the P3MT NWs are studied throughout the whole process at solid state. In addition, the correlation between the PL enhancement and the double helix DNA with various lengths is demonstrated.

DNA-embedding Schiff base molecule assemblies: an efficient biological detection approach based on clustering-triggered emission

“…13–15 For example, approaches based on the conformational change of π-conjugated polymers upon DNA hybridization have been developed by numerous scholars. 16–18…”

“…[13][14][15] For example, approaches based on the conformational change of p-conjugated polymers upon DNA hybridization have been developed by numerous scholars. [16][17][18] Recently, the hybrid assemblies composed of an organic semiconducting molecule, tri(8-hydroxyquinoline) aluminum (Alq 3 ), and single-strand DNAs (ssDNAs) prepared by Ahn and co-workers were proven to recognize specific tDNA molecules. 19,20 Recently it was found that Schiff base compounds, a class of organic small molecules, exhibit excellent performance in the sensing of metal ions, anions, thiols, nitrogen-containing compounds, pH change, and bacteria.…”

Multifunctional Polydiacetylenic Complex Films: Preferential Host-Guest Interaction with Specific Small Molecules and Recognition of Aldehyde Derivatives

“…The conformation control and tunable properties afforded by supramolecular materials would be particularly useful for functional materials containing conjugated polymers [10][11][12][13]. Owing to extended π-electron delocalization along their backbones, conjugated polymers exhibit optical properties for applications [14][15][16].…”

Luminescent Organic Barcode Nanowires for Effective Chemical Sensors

“…Polymeric π-conjugated compounds have been widely explored owing to their novel electrical and optical properties. These fascinating properties allow for various technological applications, such as organic light-emitting diodes (OLEDs), organic field-effect transistors (OFETs), organic photovoltaic cells (OPVCs), electrochromic devices, field emission displays, and actuators [5,6,7,8,9,10,11]. Facile and reliable methods for the detection of biological/chemical substances are important for scientific research due to their substantial application in sensor development.…”