Photomodulation of Enzymes

Hug, Daniel

doi:10.1007/978-1-4757-0896-7_14

Cited by 3 publications

(3 citation statements)

References 53 publications

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“…A possible photomodulation of other mitochondrial enzymes (42,43) is not considered here because as a rule they do not contain known chromophores absorbing at 700–900 nm. One can suggest that measured changes in glutamate dehydrogenase properties under irradiation at 632.8 nm (43) are due to absorbance of a semiquinone form of this flavoprotein.…”

Section: Discussionmentioning

confidence: 99%

A Novel Mitochondrial Signaling Pathway Activated by Visible‐to‐near Infrared Radiation^¶

Karu

Pyatibrat

Afanasyeva³

2004

Photochem & Photobiology

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The number of cells attached to glass substratum increases if HeLa cell suspension is irradiated with monochromatic visible‐to‐near infrared radiation before plating (the action spectrum with maxima at 619, 657, 675, 700, 740, 760, 800, 820, 840 and 860 nm). Treating of cell suspension with sodium azide (2 × 10−5M), sodium nitroprusside (5 × 10−5M), ouabain (1 × 10−6M) or amiloride (1.7 × 10−5M) before irradiation significantly modifies the spectrum of cell attachment enhancement. A light‐induced mitochondrial signaling pathway can be regulated by small ligands directly binding to the catalytic center of cytochrome c oxidase (N3, NO) as well as by chemicals specifically binding to plasma membrane enzymes (ouabain, amiloride). The comparative analysis of action spectra allows the conclusions that first, CuA and CuB chromophores of cytochrome c oxidase could be involved as photoacceptors and second, various signaling pathways (reaction channels) between cytochrome c oxidase and cell attachment regulation are at work.

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Section: Discussionmentioning

confidence: 99%

A Novel Mitochondrial Signaling Pathway Activated by Visible‐to‐near Infrared Radiation^¶

Karu

Pyatibrat

Afanasyeva³

2004

Photochem & Photobiology

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“…[15][16][17] Although the effects of coherent and noncoherent light on biological systems have been widely investigated, the mechanisms underlying photostimulation remain to be fully established. …”

Section: Discussionmentioning

confidence: 99%

Studies on the in vitro inversion of flurbiprofen

1997

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“…Activation or inactivation has been proved for different enzymes, for example, the direct reactions of enzymes to light, which manifest in substrate production, inhibitor dissociation, in chemical reactions of amino acids, luminescence of chromophores or enzyme substrates. Indirect effects of photomodulation of enzymes realize through expression of genes, phytochromes, synthesis of proteins and membranes [25].…”

Section: Hsp-proteinsmentioning

confidence: 99%

Механізми Первісної Рецепції Електромагнітних Хвиль Оптичного Діапазону Як Біофізична Основа Терапії Поляризованим Світлом

Hulyar¹

2015

MIE

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An existence of separate functional system of electromagnetic balance regulation has been substantiated and a working conception of light puncture has been formulated. As a basis, there is a possibility to use the acupuncture points for input of biologically necessary electromagnetic waves into the system of their conductors in a body that might be considered as a transport facility for energy ofthe polarized electromagnetic waves. Zones-recipients are organs having an electromagnetic disbalance due to excess of biologically inadequate radiation and being the targets for peroxide oxidation, foremost, a body has the neurohormonal and immune regulatory systems. Electromagnetic stimulation or modification of functions of the zones-recipients determines achievement of therapeutic and useful effects, and their combination with local reparative processes allows attaining a clinical goal. We represent own and literary experimental data about development of physiological responses (analgesia, bronchospasm control, immune stimulation and inhibition of peroxide oxidation of lipids) to BIOPTRON-light exposure on the acupuncture points or biologically active zones. We show the experimental facts in support of a hypothesis that a living organism can perceive an action of the electromagnetic waves of optical range not only via the visual system, but also through the off-nerve receptors (specific energy-sensitive proteins detecting critical changes of energy in cells and functioning as the "sensory" cell systems), as well as via the acupuncture points. This confirms an important role of the electromagnetic waves of optical range in providing normal vital functions of living organisms. A current approach to BIOPTRON light therapy consists in combined (local and system) exposure of the electromagnetic waves within the biologically necessary range.

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Photomodulation of Enzymes

Cited by 3 publications

References 53 publications

A Novel Mitochondrial Signaling Pathway Activated by Visible‐to‐near Infrared Radiation^¶

A Novel Mitochondrial Signaling Pathway Activated by Visible‐to‐near Infrared Radiation^¶

Studies on the in vitro inversion of flurbiprofen

Механізми Первісної Рецепції Електромагнітних Хвиль Оптичного Діапазону Як Біофізична Основа Терапії Поляризованим Світлом

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Photomodulation of Enzymes

Cited by 3 publications

References 53 publications

A Novel Mitochondrial Signaling Pathway Activated by Visible‐to‐near Infrared Radiation¶

A Novel Mitochondrial Signaling Pathway Activated by Visible‐to‐near Infrared Radiation¶

Studies on the in vitro inversion of flurbiprofen

Механізми Первісної Рецепції Електромагнітних Хвиль Оптичного Діапазону Як Біофізична Основа Терапії Поляризованим Світлом

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A Novel Mitochondrial Signaling Pathway Activated by Visible‐to‐near Infrared Radiation^¶

A Novel Mitochondrial Signaling Pathway Activated by Visible‐to‐near Infrared Radiation^¶