The possibility of the photonuclear production of radioisotopes 111 In, 117m Sn, 124 Sb, and 177 Lu is discussed. Reaction yields were measured by the gamma-activation method. The enriched tin isotopes 112,118 Sn and Te and HfO 2 of natural isotopic composition were used as targets. The targets were irradiated at the linear electron accelerator of Alikhanian National Science Laboratory (Yerevan) at the energy of 40 MeV. The experimental results obtained in this way reveal that the yield and purity of radioisotopes 111 In and 117m Sn are acceptable for their production via photonuclear reactions. Reactions proceeding on targets from Te and HfO 2 of natural isotopic composition and leading to the formation of 124 Sb and 177 Lu have small yields and are hardly appropriate for the photoproduction of these radioisotopes even in the case of enriched targets.