Photopolymerization of Poly(ethylene Glycol) Diacrylate in Supercritical Carbon Dioxide

Meng, Zhun; Nie, Jun; He, Yong

doi:10.3724/sp.j.1105.2010.09257

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…When exposed to UV light, the TPO in PEGDMA produces free radicals. Free radicals [18,19] are vital in the cross-linking reaction; they combine and react with monomer molecules by opening carboncarbon bonds in the PEGDMA monomer. Through this reaction, the PEGDMA solution was converted to a solid layer with the designed patterns.…”

Section: Layout and Fabrication Of Hydrogel Microstructuresmentioning

confidence: 99%

Construction of Microenvironment Structures for the Study of Cell Behavior using DMD-based Optical Projection Lithography

Liu

2018

2018 IEEE 18th International Conference on Nanotechnology (IEEE-NANO)

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The construction of the microenvironment is of great importance for the study of cell behaviors such as motility and viability. The morphology and mechanical properties of cells can be affected by the microenvironment and interactions between cells. There have been numerous studies on cell-cell and cell-microenvironment interactions. However, these studies are generally time-consuming and complicated for the following reasons: firstly, constructing the microenvironment is complex, as the microenvironment itself is complicated; secondly, the internal characteristics of different components of the microenvironment are highly variable and difficult to simulate. Using a digital micromirror device (DMD)-based optical projection lithography system, we have developed a new method for cell studies: by employing a digital dynamic mask, poly(ethylene glycol) dimethacrylate (PEGDMA)-based hydrogels could be easily designed with a wide variety of patterns. Those structures can be rationally designed to be functional, as different modules can mimic the microenvironment and restrict the migration of cells. Furthermore, 4% paraformaldehyde can be mixed into the PEGDMA and cured using UV exposure. Paraformaldehyde in hydrogels had a moderate impact on the viability of cells.

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Section: Layout and Fabrication Of Hydrogel Microstructuresmentioning

confidence: 99%

Construction of Microenvironment Structures for the Study of Cell Behavior using DMD-based Optical Projection Lithography

Liu

2018

2018 IEEE 18th International Conference on Nanotechnology (IEEE-NANO)

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“…Research on hydrogel microfabrication has become a hot topic because of its extensive application in biological engineering. Particularly, poly(ethylene glycol) diacrylate (PEGDA) [1] is a commonly used hydrogel because of its biocompatibility and excellent mechanical properties. PEGDA has been widely used in various fields such as drug delivery [2,3], biosensing [4], tissue engineering [5,6], directed cell migration [7], and fabrication of micropillar arrays [8].…”

Section: Introductionmentioning

confidence: 99%

Fabrication of microstructures using the DMD-based modulating projection printing method

Wang

Liu

2015

10th IEEE International Conference on Nano/Micro Engineered and Molecular Systems

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Patterned microstructures of hydrogels have attracted significant attention due to an increasing need for developing scaffolds for tissue engineering, as carriers for drug delivery, and as extracellular matrices for biological studies. However, current tissue engineering approaches lack the flexibility required for developing complex two or threedimensional (2D/3D) microstructures, which are used to impart suitable cell mechanical microenvironments. In this paper, we present an ultraviolet (UV) light curing method based on a digital mirror device-based modulating projection printing (DMPP) system for fabricating patterned poly(ethylene glycol) diacrylate (PEGDA) hydrogel microstructures. With programmable UV exposure, polymerisation of the PEGDA solution can be induced to create 2D/3D microstructures with high biocompatibility. The main advantage of DMPP is that it is a mask-free method. In addition, the efficiency of the DMPP method is much higher than other methods for patterning PEGDA microstructures. The duration of UV exposure was less than 10 s. In the experiments described below, several types of microstructure arrays have been fabricated. These initial results show that the DMPP method can be used for fabricating highly complex microstructures with controlled accuracy.

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Supercritical carbon dioxide assisted synthesis of amphiphilic graft copolymers based on poly(styrene-co-maleic anhydride) with methoxyl poly(ethylene glycol) side chains

Wang

Zhu

et al. 2011

Chin J Polym Sci

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Photopolymerization of Poly(ethylene Glycol) Diacrylate in Supercritical Carbon Dioxide

Cited by 4 publications

References 8 publications

Construction of Microenvironment Structures for the Study of Cell Behavior using DMD-based Optical Projection Lithography

Construction of Microenvironment Structures for the Study of Cell Behavior using DMD-based Optical Projection Lithography

Fabrication of microstructures using the DMD-based modulating projection printing method

Supercritical carbon dioxide assisted synthesis of amphiphilic graft copolymers based on poly(styrene-co-maleic anhydride) with methoxyl poly(ethylene glycol) side chains

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