Photoprotective Activity of Ipomoea horsfalliae Flower Extract

Abstract

In this work, we studied the potential photoprotective effect of Ipomoea horsfalliae Hook., Convolvulaceae, flower extract. Ipomoea horsfalliae is a plant that grows in tropical and subtropical regions. I. horsfalliae ethanolic extracts were analyzed by ultra-high efficiency liquid chromatography-high-resolution mass spectrometry. Dicaffeoylquinic acid, chlorogenic acid, scopoletin, glycosylated cyanidin, pelargonidin, and kaempferol were identified as major components of I. horsfalliae flower extract. In vitro biossays were used to evaluate cytotoxic and sensitizing effects of the extracts, and their photoprotective effect was evaluated in BALB/c mice. Morphological and histopathological observation of the skin tissues from mice suggested that UV-B-induced edema was significantly inhibited by treatment with I. horsfalliae flower extract. It was not cytotoxic for both cancerous and normal cells, and no sensitizing effect was observed. I.horsfalliae flower extract appears to be a good starting point for research programs leading to the development of natural skin care products.

Exploring the Potential of Extracts from Sloanea medusula and S. calva: Formulating Two Skincare Gels with Antioxidant, Sun Protective Factor, and Anti-Candida albicans Activities

“…Currently, the photoprotective properties of extracts [ 58 ], essential oils [ 29 ], and secondary metabolites [ 59 ] are being explored, and the antifungal activity of these natural extracts [ 60 ] and compounds [ 61 ] has highlighted the potential of Colombian flora for the development of topical formulations.…”

Flower Extracts from Ornamental Plants as Sources of Sunscreen Ingredients: Determination by In Vitro Methods of Photoprotective Efficacy, Antigenotoxicity and Safety

“…Conversely, the extract obtained from I. horsfalliae, a species with previously reported sunscreen properties [ 40 ], was shown to be cytotoxic and genotoxic to human fibroblast cells. Little is still known about the genotoxicity of the major compounds (chlorogenic acid, dicaffeoylquinic acid, and scopoletin) of this extract.…”

“…For each specimen, undamaged and fully developed flowers were dried in an Advantage Plus Tray Lyophilizer (Virtis Co., Gardiner, ME, USA) and were used for solvent extraction as indicated by Sierra et al [ 40 ]. In brief, dried flowers (1 g) were mixed with acidified ethanol solution (20 mL, 0.5% HCl, 1:1 v / v ) and put for 5 min in an S15H ultrasound bath (Elmasonic, Singen, Germany).…”

Color, Antioxidant Capacity and Flavonoid Composition in Hibiscus rosa-sinensis Cultivars

“…Solvent extraction was performed according to Sierra et al [ 57 ]. Three fresh petals of each H. rosa-sinensis cultivar (0.5 g) were immersed in an ethanol solution (20 mL, 0.5% HCl, 1:1 v/v in type I water) using an ultrasonic bath (15 min, 50 °C, Elma-sonic S15H, Singen, Germany).…”