Photoprotective and Antiinflammatory Effects of Topical Glycolic Acid

Perricone, Nicholas V.; DiNardo, Joseph C

doi:10.1111/j.1524-4725.1996.tb00343.x

Cited by 62 publications

(49 citation statements)

References 2 publications

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“…Ascorbic acid or vitamin C, the most well known anti-oxidant, poses anti-inflammatory properties that are appraisal in the treatment of acne [63]. It scavenges the generated radicals terminating inflammation accordingly.…”

Section: Vitamin Cmentioning

confidence: 99%

Therapeutic agents and herbs in topical application for acne treatment

Kanlayavattanakul

Lourith

2011

Intern J of Cosmetic Sci

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SynopsisAcne vulgaris suppresses an individual's self-confidence by causing distress with regard to physical appearance, which affects a significant number of individuals during puberty and is delineated by adolescence. Several treatments have been introduced to decrease the aesthetic and psychological problems caused by acne. The topical application of therapeutic agents has been found to be more feasible than hormonal treatment and laser therapy. The ingredients in topical acne treatments, particularly herbs and naturally derived compounds, have received considerable interest as they have fewer adverse effects than synthetic agents. Ré suméL'acné vulgaire touche à l'assurance d'un individu en causant une détresse face à son apparence physique. Elle affecte un nombre important d'individus pendant la puberté et est associée à l'adolescence. Plusieurs traitements ont été proposés pour diminuer les problèmes esthétiques et psychologiques causés par l'acné. L'application topique d'agents thérapeutiques a été estimée plus aisée qu'un traitement hormonal et une thérapie laser. Les ingrédients des traitements topiques de l'acné, particulièrement les plantes et les composés naturels dérivés ont suscité un intérêt considérable par leurs moindres effets indésirables que les ingrédients synthé-tiques.

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Section: Vitamin Cmentioning

confidence: 99%

Therapeutic agents and herbs in topical application for acne treatment

Kanlayavattanakul

Lourith

2011

Intern J of Cosmetic Sci

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“…29,30) Additionally, glycolic acid can provide a protective anti-oxidative effect on photodamaged skin, 31) increase the hyaluronic acid level, and increase the number and quality of elastic fiber tissues. [32][33][34] Therefore, 10H2DA may exert its pharmacological activities through a mechanism similar to that of glycolic acid.…”

Section: Discussionmentioning

confidence: 99%

Identification of a Collagen Production-promoting Factor from an Extract of Royal Jelly and Its Possible Mechanism

Koya‐Miyata

Okamoto

Ushio

et al. 2004

Bioscience, Biotechnology, and Biochemistry

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We have previously shown that royal jelly (RJ) promoted collagen production by skin fibroblasts in the presence of ascorbic acid-2-O-alpha-glucoside (AA-2G). In this study, we purified the honeybee RJ-derived collagen production-promoting factor (HBRJ-CPF) from an alkali-solubilized fraction of RJ by C18 reverse-phase column chromatography. The elution profile by the C18 column chromatography and the molecular mass of the purified HBRJ-CPF material coincided with those of 10-hydroxy-2-decenoic acid (10H2DA). We then examined the collagen productionpromoting activities of several commercially available fatty acids contained in RJ. We found that 10H2DA and 10-hydroxydecanoic acid increased the collagen production in a dose-dependent manner. Furthermore, 10H2DA induced the fibroblast cell line, NHDF, to produce transforming growth factor-1 (TGF-1) which is an important factor for collagen production. As expected, the collagen production-promoting activity of 10H2DA was neutralized by the anti-TGF-1 antibody. These result suggest that HBRJ-CPF identified as 10H2DA promoted the collagen production of AA-2G-treated fibroblasts by inducing TGF-1 production.

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“…Vitamin C is usually found in human skin, but it is rapidly lost in inflammatory processes. Topical vitamin C supplement for the skin, through lipid molecules, can be beneficial in dermatological treatment (Perricone, 1993). The topical application of vitamin C partially restores the anatomical structure of the epidermal-dermal junction in young skin and it increases the number of nutritive capillary loops in the papillary dermis (Kirsten et al, 2004).…”

Section: Introductionmentioning

confidence: 99%