Photorejuvenation for Asian Skin by Intense Pulsed Light

Negishi, Kei; Tezuka, Yukiko; Kushikata, Nobuharu; Wakamatsu, Shingo

doi:10.1046/j.1524-4725.2001.01002.x

Cited by 121 publications

(96 citation statements)

References 19 publications

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“…The IPL, which emits a broadband of visible light from a non-coherent filtered flashlamp, produces only photothermal effects. Recent studies that investigated the use of IPL to remove lentigines in Asians confirmed their effectiveness with a low risk of PIH [12,13]. These observations suggest that the photomechanical effect of Q-switched laser for the treatment of lentigines in Asians may not be desirable.…”

Section: Discussionmentioning

confidence: 96%

Q‐switched ruby versus long‐pulsed dye laser delivered with compression for treatment of facial lentigines in Asians

et al. 2005

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Background and Objectives: Q-switched lasers have been used for the treatment of lentigines but postinflammatory hyperpigmentation (PIH) can be an issue especially in Asians. The 595 nm long-pulsed dye laser (LPDL) has been used for the treatment of vascular lesions and although it is well absorbed by oxyhemoglobin, it is also absorbed by melanin. To use this device for the treatment of facial lentigines, we attached a flat glass lens to the tip of the laser's handpiece, allowing compression of the skin during treatment. In doing so, eliminated the absorption by oxyhemoglobin. This prospective study aims to compare the efficacy and complications of such an approach to the use of Q-switched ruby laser (QSRL) in the treatment of facial lentigines in Asians. Study Design/Materials and Methods: Eighteen Asian patients (1 male, 17 female) with facial lentigines Fitzpatrick skin types III-IV were enrolled. One of the lentigines present was treated with LPDL by compression method and the other one was treated with QSRL. A LPDL emitting wavelength of 595 nm, spot size of 7 mm was used, with fluence between 10 and 13 J/cm 2 and pulse duration of 1.5 milliseconds. Cryogen spray cooling was not used. A 694 nm QSRL was used with a spot size of 4 mm, fluence of 6-7 J/cm 2 , and pulse duration of 30 nanoseconds. Lightening of the lesions was assessed by reflectance spectrometer Erythema, hypo-or hyperpigmentation and scarring were also assessed by clinical examinators. Results: The degree of clearing achieved with the two lasers was 70.3% and 83.3% for QSRL and LPDL, respectively. All QSRL treated areas developed erythema whereas only 4 of 18 LPDL treated areas developed erythema. Hyperpigmentation was seen in four patients after QSRL, but not after LPDL. There was no scarring or hypopigmentation. Conclusions: LPDL delivered with a compression method is more effective than QSRL for facial lentigines. Complications after LPDL treatment were substantially less frequent than after QSRL. The addition of compression technique may allow ''vascular'' pulsed dye laser to be used for treating a variety of pigmented lesions. Lasers Surg. Med. 38:94-97, 2006. ß 2005 Wiley-Liss, Inc.

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Section: Discussionmentioning

confidence: 96%

Q‐switched ruby versus long‐pulsed dye laser delivered with compression for treatment of facial lentigines in Asians

et al. 2005

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“…16 In 6 of the studies, blinded independent observers were used to evaluate clinical photographs before and after treatment. 6,7,10,12,15,16 In one study, only the treating physician and the patient evaluated the clinical benefit, 14 and in another study, only the subjects graded the effect of the treatment. 13 In one study, the participating physicians performed the evaluations of clinical improvement.…”

Section: Resultsmentioning

confidence: 99%

“…Negishi et al 14 reported on the use of intense pulsed light for the rejuvenation of skin in an Asian population. A total of 97 patients between the ages of 22 and 70 years were treated, and the results were rated by both patients and physicians according to a 4-point scale.…”

Section: Intense Pulsed Lightmentioning

confidence: 99%

Clinical Efficacy of Devices for Nonablative Photorejuvenation

Leffell¹

2002

Arch Dermatol

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“…Decrease of melanin-pigmented epidermal keratinocytes in the basal layer: This is believed to be the result of the fact that pigmentation existing in the epidermal stratum basale in the area affected by the lichen pilaris was photothermally damaged by the Nd:YAG laser through selective photothermolysis. In treatment using intense pulsed light systems which are typically used for less-invasive treatment, epidermal pigmentation in the basal layer has been shown to be photothermally damaged by the same mechanism 11,16) and it has also been reported that epidermal mother keratinocytes are induced to enter a higher proliferative state, thereby forcing daughter melanocytes with QS-Nd:YAG for Lichen Pilaris a b …”

Section: Case Reportmentioning

confidence: 99%

Treatment of lichen pilaris with a Q-switched Nd:YAG laser in quasi long-pulsed mode: A case report (a secondary publication)

Ueda¹

2014

LASER THERAPY

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Even though lichen pilaris has been conventionally treated with topical preparations such as urea ointment, salicylic acid, petrolatum and vitamin A ointment and the like, none of these therapeutic approaches has been reported to achieve good and consistent results. In addition, this may be a disorder for which the necessity for treatment tends to be underestimated since the symptoms are is said to decrease with age and almost disappear spontaneously by the time the patients are in their 30s. However, spontaneous regression can take a longer period of time till full disappearance, prompting quite a few patients to visit clinics from the cosmetic perspective of the condition. The Q-switched Nd: YAG laser (QSNY) has been wellreported for the successful treatment of pigmented cutaneous lesions and for skin rejuvenation. The present study therefore trialled the application of the QSNY in a case of lichen pilaris. Only a few treatments have been reported as significantly effective, so often natural resolution over time is the only option. The present study examined the use of a 1064 nm Q-switched Nd:YAG laser (QSNY) in quasi long-pulsed mode, in an attempt to treat a case of lichen pilaris. Subject and Methods Subject and condition Subject and Methods:A 33-year-old male presented with light-brown aggregated papules observed on both sides of the upper arms. The affected areas were treated every other week (QSNY, pulse width 300 µs, pulse energy 3.0 J/cm², spot size 6 mm and repetition rate 10 Hz). Clinical photography was taken of the lesions at baseline and three months after the final treatment in addition to macrophotography and 3-D photography, biopsies being taken at both time points for histological comparison. Results:The clinical photography and objective image evaluation demonstrated shrinkage of pores and improvement of the unevenness of the skin. Histological examination suggested that the effect of the micropulsed QSNY on the horny layer, epidermal keratinocytes and dermal collagen resulted in a peeling effect and increased dermal collagen density, which eventually led to the shrinkage of the pores and improvement of the skin condition. Conclusions:The results of this single patient case report suggest that the micropulsed QSNY could be an effective treatment option for lichen pilaris, improvement of which is often difficult.Further studies with an appropriately-sized population are merited to confirm these preliminary results.

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Photorejuvenation for Asian Skin by Intense Pulsed Light

Abstract: Photorejuvenation using IPL is a completely safe and effective procedure even for Asian skin. It will be increasingly used for skin rejuvenation in the future.

Cited by 121 publications

References 19 publications

Q‐switched ruby versus long‐pulsed dye laser delivered with compression for treatment of facial lentigines in Asians

Q‐switched ruby versus long‐pulsed dye laser delivered with compression for treatment of facial lentigines in Asians

Clinical Efficacy of Devices for Nonablative Photorejuvenation

Treatment of lichen pilaris with a Q-switched Nd:YAG laser in quasi long-pulsed mode: A case report (a secondary publication)

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