Photoselective Vaporization of the Prostate for the Treatment of Benign Prostatic Hyperplasia: 12-Month Results From the First United States Multicenter Prospective Trial

Te, Alexis E.; Malloy, Terrence R.; Stein, Barry S.; Ulchaker, James; Nseyo, Unyime O.; Hai, Mahmood A.; Malek, Reza S.

doi:10.1097/01.ju.0000139541.68542.f6

Cited by 223 publications

(145 citation statements)

References 11 publications

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“…Incontinence rates reported with the HoLEP range from 0.5 10 to 3%, 12 whereas incontinence rates reported with the PVP using the 80 W KTP laser range from 0 to 1.4%. 13 In terms of retrograde ejaculation, the two cases reported in this study occurred in patients with a median lobe, which was lasered in a non-contact mode. This potentially could have caused the damage to the circular muscle fibres at bladder neck.…”

Section: Discussionmentioning

confidence: 79%

Preliminary results on selective light vaporization with the side-firing 980 nm diode laser in benign prostatic hyperplasia: an ejaculation sparing technique

Leonardi¹

2009

Prostate Cancer Prostatic Dis

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This study examined efficacy and safety of the 980 nm side-firing diode laser operating at a power of 100 W in patients with lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). Patients were selected for surgery on the basis of maximum urinary flow rate (Qmax) p15 ml/s or transvesically measured post-voiding residual volume (PVR) 4100 ml in conjunction with an International Prostate Symptom Score (IPSS) 47. Laser therapy was conducted under spinal anaesthesia. Qmax, IPSS, prostate volume, PVR, IPSS-Quality of Life (QoL) questionnaire and ejaculatory function were measured at baseline and at 1, 3, 6 and 12 months post-laser therapy. A total of 52 consecutive patients aged 52-65 years with mean (s.d.) prostate volume of 45.14 (9.15) g were treated. All patients were able to leave the hospital at a mean (s.d.) of 5 (2) h after the procedure. Mean (s.d.) follow-up was 100 (75.49) days. A significant reduction in IPPS was reported at 1 month (Po0.0001) and this was maintained through to 6 months. Significant durable improvements in Qmax, PVR and IPSS-QoL score were also reported for all patients (Po0.0001). No severe complications were reported, including any cases of urinary incontinence or significant irritative symptoms. None of the patients complained of a worsening of erectile function. This early experience in a pilot study with the 980 nm diode laser seems promising in the short-term and long-term outcome is being monitored.

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Section: Discussionmentioning

confidence: 79%

Preliminary results on selective light vaporization with the side-firing 980 nm diode laser in benign prostatic hyperplasia: an ejaculation sparing technique

Leonardi¹

2009

Prostate Cancer Prostatic Dis

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“…Although effective, the technique can be associated with significant complications, including TUR syndrome and bleeding [3][4][5][6]. Newer technologies such as PVP offer safer and equally effective alternatives to relieve symptomatic bladder outlet obstruction [7][8][9][10][11][12][13][14][15]. Few studies however have directly examined the clinical differences between 80 W vs. 120 W PVP [17].…”

Section: Discussionmentioning

confidence: 99%

“…This technique has been shown to result in comparatively fewer complications, e.g. reduced incidence of TUR syndrome as well as bleeding [7][8][9][10][11][12][13][14][15], Improvements to the Greenlight ™ laser system have been made over time, particularly with the introduction of the 120 W HPS system in 2006. Few however have compared the clinical performance of the newer systems with their predecessors.…”

Section: Introductionmentioning

confidence: 99%

Comparison of 80 W versus 120 W 532 nm Laser Prostatectomy for BPH

Lee¹

2013

OJU

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Purpose: Improvements to photoselective vaporization of the prostate (PVP) have been made over time, particularly with the introduction of higher power systems. Few studies however have compared the performance of these systems to their predecessors. Baseline parameters were similar between the two groups except for greater median age (72.8 vs. 69.2 years, p = 0.01) and lower median PSA (2.0 vs. 3.3, p = 0.01) in the 80 W group. Median laser time was longer in the 80W group (85 vs. 51 minutes, p < 0.001) with a higher median energy utilized (253 vs. 210 kJ, p = 0.001). Final IPSS, Qmax, PVR, and PSA were equivalent between the two groups. Conclusions: In our series, PVP was safe and effective. Durable and similar improvements in symptoms and objective parameters were achieved in patients with both 80 W and 120 W laser systems. PVP with the 120 W system, however, provided faster and more efficient vaporization compared to the 80 W system.

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“…In the first large, multicenter study examining the 80-W KTP laser for the treatment of BOO, Te et al [34] followed 145 patients over 1 year and found durable improvements in all urinary metrics and significant decreases in prostate volume by ultrasound. No patient required a blood transfusion, and only 3% had post-operative urinary retention.…”

Section: -W Ktp Lasermentioning

confidence: 99%

Current Laser Therapies for the Treatment of Benign Prostatic Hyperplasia

2016

IJSR

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Abstract:The gold standard for symptomatic relief of bladder outlet obstruction secondary to be-nign prostatic hyperplasia has traditionally been a transurethral resection of the pros-tate (TURP). Over the past decade, however, novel laser technologies that are patient friendly as compared to the con-ventional TURP have been developed. As part of the ongoing quest to minimize complica-tions, shorten hospitalization, improve resection time, and most importantly reduce mortality, laser prostatectomy has continually evolved. Today, there are more varia-tions of laser prostatectomy, each with several differing surgical techniques. Although abundant data are available confirming the safety and feasibility of the various laser systems, future randomized-controlled trials will be necessary to verify which techni-que is superior. In this article, we describe the most common modalities used to perform a laser prostatectomy, mainly, the holmium laser and the potassium-titanyl-phosphate lasers. We also highlight the physical and clinical characteristics of each technology with a review of their efficacy.

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Photoselective Vaporization of the Prostate for the Treatment of Benign Prostatic Hyperplasia: 12-Month Results From the First United States Multicenter Prospective Trial

Abstract: PVP is a unique, safe and effective outpatient modality that provides immediate symptomatic and urodynamic relief of bladder outlet obstruction secondary to BPH. Long-term followup is needed to validate further the maintenance of clinical efficacy beyond 1 year.

Cited by 223 publications

References 11 publications

Preliminary results on selective light vaporization with the side-firing 980 nm diode laser in benign prostatic hyperplasia: an ejaculation sparing technique

Preliminary results on selective light vaporization with the side-firing 980 nm diode laser in benign prostatic hyperplasia: an ejaculation sparing technique

Comparison of 80 W versus 120 W 532 nm Laser Prostatectomy for BPH

Current Laser Therapies for the Treatment of Benign Prostatic Hyperplasia

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