Photostimulated imprinted polymers: a light-regulated medium for transport of amino acids

Abstract

A tryptophan imprinted merocyanine copolymer exhibits transport properties towards the polymer-registered substrate; the photoisomerized spiropyran copolymer is non-permeable towards the substrate and the imprinted information is erased.

Molecular imprinting science and technology: a survey of the literature for the years up to and including 2003

“…with a constantly replenished receiver solution). 1357 Transport of Trp was observed in water, which could be switched off by visible light. The light converted the merocyanine into its spiropyran isomer, though the change in transport may be more due to changes in the charge state of the polymer than subtle imprinting effects-selectivity was only studied in comparison with very different substrates.…”

The Fabrication of a Photoresponsive Molecularly Imprinted Polymer for the Photoregulated Uptake and Release of Caffeine

“…Rate constants for the trans → cis and cis → trans isomerization of the azobenzene chromophores within the MIP material were found to be 3.33 × 10 -4 and 10.37 × 10 -4 s -1 , respectively, which are, respectively, 2.3 and 1.4-fold smaller than the corresponding photoisomerization processes of MPABA monomer in solution. The slower isomerization rate is likely to be caused by 10, 20, 30, 40, 50, 60, 70, 80, 90, 100, and 110 min; b) subsequent cis → trans isomerization by irradiation at 440 nm for 5,10,15,20,25,30,35,40,45,50,55,60,65, and 70 min. Insets: the kinetics of the photoisomerization (monitored at 339 nm).…”

“…They used an acrylatederivatized merocyanine monomer for the imprinting of tryptophan in a molecularly imprinted membrane, which exhibited photocontrollable selective transport properties towards the imprinted amino acid. [15] In this work, an azobenzene-based, photoswitchable functionalized monomer, 4-[(4-methacryloyloxy)phenylazo]benzoic acid (MPABA) (Scheme 1), reported by Haitjema et al, [9a] was employed to fabricate a bulk MIP material using caffeine as a model molecular template. The MIP material was able to release and take up caffeine upon irradiation at 365 and 440 nm, respectively.…”

Electroanalytical Applications of Metallic Nanoparticles and Supramolecular Nanostructures

“…The imprinting of organic or inorganic polymers with molecular recognition sites is a versatile process to prepare polymer matrices with specific and selective binding properties [33]. Such matrices found different applications in chromatographic separations [34], controlled release processes [35] and sensor applications [36]. In general, the imprinting process involves the polymerization of monomer units in the presence of a target substrate, or a molecular analog to the target substrate, under crosslinking conditions, and the subsequent removal of the target substrate, a process that yields molecularly imprinted polymers that include rigidified molecular contours for the binding of the substrate.…”