Phototherapeutic keratectomy for recurrent erosion syndrome in anterior basement membrane dystrophy11None of the authors has any financial interest in the entities described in this article.

Cavanaugh, Timothy; Lind, Diana M.; Cutarelli, Paul E.; Mack, Robert J.; Durrie, Daniel S.; Hassanein, Khathab M; Graham, Charles E.

doi:10.1016/s0161-6420(99)00540-0

Cited by 81 publications

(19 citation statements)

References 12 publications

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“…It has been shown that excimer photorefractive keratectomy and laser in situ keratomileusis alter the wound healing response of the cornea [11]. The effects of PTK on wound healing have been described and are indeed desired in the treatment of RCE to improve the postoperative epithelial adhesion [5, 12], but there is no known effect of excimer laser treatment on the speed of corneal epithelialization. To avoid any bias between the groups, both groups were treated with the same laser settings under the same conditions, and care was taken to apply local anesthesia and fluorescein staining necessary for the photographs in equal dosages at the same time intervals.…”

Section: Discussionmentioning

confidence: 99%

Corneal Re-Epithelialization following Phototherapeutic Keratectomy for Recurrent Corneal Erosion as in vivo Model of Epithelial Wound Healing

et al. 2009

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Background: This placebo-controlled double-blind study examined the suitability of recording corneal epithelialization after phototherapeutic keratectomy (PTK) as a model of epithelial wound healing. Methods: Eighteen patients with recurrent corneal erosion were randomized into 2 groups, and received PTK with a 7-mm ablation zone. Postoperatively, one group was treated with an ointment containing 5% dexpanthenol and the other with the ointment vehicle without dexpanthenol. The epithelial lesions were recorded by digital slit-lamp photographs with fluorescein staining at fixed intervals until epithelial closure. The size of the epithelial defect was measured, and the average time until epithelial closure was calculated. Reliability of measurements was tested by calculating Cronbach’s α from measurements at the same point in time. Results: Photographs could be taken at all scheduled examinations. The measured size of the epithelial defects showed a high reliability (Cronbach’s α = 0.994). The average time needed for epithelial closure was 57.5 h in the treatment group and 64.8 h in the placebo group (p = 0.177). Conclusions: Planimetric measurement of slit-lamp photographs of standardized epithelial defects is an adequate method for monitoring the progress of corneal epithelial wound healing. Although wounds treated with dexpanthenol showed a slightly shorter average healing time, the difference to the placebo was not significant.

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Section: Discussionmentioning

confidence: 99%

Corneal Re-Epithelialization following Phototherapeutic Keratectomy for Recurrent Corneal Erosion as in vivo Model of Epithelial Wound Healing

et al. 2009

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“…While Baryla et al stated that a higher proportion of dystrophic cases led to increased recurrence rates, Pogorelov et al observed no recurrences in a study of MDF patients [25]. With regard to surgical re-treatment rates after PTK for RCE, Cavanaugh et al found a re-treatment rate of 13.8 % in MDF patients after PTK for RCE [26]. Dinh and co-workers investigated a heterogeneous population of patients with various dystrophic syndromes and reported a surgical re-treatment rate of 8.3 % [11].…”

Section: Main Findingsmentioning

confidence: 99%

Phototherapeutic keratectomy (PTK) for treatment of recurrent corneal erosion: Correlation between etiology and prognosis – prospective longitudinal study

Dedes

Faes

Schipper

et al. 2015

Graefes Arch Clin Exp Ophthalmol

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“…[41–48] It is also tried in cases of Fuchs’ endothelial dystrophy for subepithelial scarring or for removal of a substantial part of the stroma, to reduce the load on the endothelium. [440] All these indications are done with a varying success rate and a varying rate of recurrence.…”

Section: Therapeutic Indications [Table 1]mentioning

confidence: 99%

“…[4152–54] Early recurrences are noted at six-to-nine months or a year or more. [41525556]Granular Dystrophy: PTK is the first line of treatment as recurrence is slow. [104357] Also, the ocular surface health is better after PTK.…”

Section: Therapeutic Indications [Table 1]mentioning

confidence: 99%

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Phototherapeutic keratectomy

Rathi

Vyas

Sangwan

2012

Indian J Ophthalmol

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Phototherapeutic keratectomy (PTK) is done regularly for anterior corneal diseases such as corneal dystrophies, corneal degenerations, scars, and band-shaped keratopathy. The various indications include both therapeutic and visual. The aim of this article is to discuss the therapeutic indications for PTK, the specific technique pertaining to a specific etiology, the various other procedures like amniotic membrane graft combined with PTK or PTK being done for recurrences in the grafts, and PTK done before cataract surgery when the anterior corneal pathology coexists with the cataract. Post PTK management such as healing of an epithelial defect, use of steroids in the post PTK period, recurrences of primary disease pathology, and infections, will be discussed. Methods of literature search: A Medline search was carried out for articles in the English language, with the keywords, phototherapeutic keratectomy, band-shaped keratopathy, spheroidal degeneration, scars, bullous keratopathy, and corneal dystrophy. The relevant references are mentioned here.

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Phototherapeutic keratectomy for recurrent erosion syndrome in anterior basement membrane dystrophy11None of the authors has any financial interest in the entities described in this article.

Cited by 81 publications

References 12 publications

Corneal Re-Epithelialization following Phototherapeutic Keratectomy for Recurrent Corneal Erosion as in vivo Model of Epithelial Wound Healing

Corneal Re-Epithelialization following Phototherapeutic Keratectomy for Recurrent Corneal Erosion as in vivo Model of Epithelial Wound Healing

Phototherapeutic keratectomy (PTK) for treatment of recurrent corneal erosion: Correlation between etiology and prognosis – prospective longitudinal study

Phototherapeutic keratectomy

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