Phototherapy for Neonatal Jaundice

Tan, Keng Leong

doi:10.1016/s0095-5108(18)30506-2

Cited by 64 publications

(51 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A greater fall in bilirubin level has been described in association with a higher level at admission. 10,13 In agreement with such investigations, the present study showed a stronger association between decrease in bilirubin after 24 hours of therapy and bilirubin level at admission in the DP group when compared to the SP group. This finding suggests that at higher levels of bilirubin DP could be more effective than SP.…”

Section: Discussionsupporting

confidence: 91%

“…The planned enrollment of 37 patients per group was based on the estimated percentage increase of 20 points in the velocity of bilirubin reduction in DP vs. SP, which, in turn, was based on a previous study with premature patients, 10 providing 80% statistical power, with an alpha of 0.05. The chi-square test and Student t test were used to compare the percentage changes.…”

Section: Discussionmentioning

confidence: 99%

“…10,11 The objective of the present study was to comparatively evaluate the efficacy of DP and SP in reducing bilirubin levels in term newborns with nonhemolytic hyperbilirubinemia, and to compare such response in relation to bilirubin levels at admission. Possible adverse effects and therapy readmissions were also analyzed.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Fototerapia simples versus dupla no tratamento de recém-nascidos a termo com hiperbilirrubinemia não-hemolítica

Silva¹,

Luco²,

Tapia³

et al. 2009

J. Pediatr. (Rio J.)

View full text Add to dashboard Cite

Objectives: To compare the effectiveness of single (1 panel) vs. double (2 panels) phototherapy in reducing nonhemolytic hyperbilirubinemia in term newborns. Methods:Term newborns with hyperbilirubinemia were prospectively randomized to receive double or single phototherapy. Bilirubin levels were measured at admission and at 12-hour intervals, as well as at a follow-up 48 hours after discharge. Results:Thirty-seven patients received single and 40 double phototherapy. The mean decrease in bilirubin level in the first 24 hours of treatment was greater in the double phototherapy group (5.1±2.2 mg/dL vs. 4.3±2.1 mg/dL), but without statistical significance (p = 0.18). Readmission rates were similar and no adverse effects were found in either group.Conclusions: Double-surface was not more effective than single-surface phototherapy in the treatment of nonhemolytic hyperbilirubinemia in term newborns. However, our results suggest that double phototherapy may be more effective in those term newborns with higher bilirubin levels at admission. is the most commonly used method, and, when bilirubin levels are close to the threshold for exchange transfusion, intensive phototherapy is indicated. 6 This can be obtained by increasing the surface area of the newborn exposed to light and the intensity of phototherapy using lateral panels, reflecting objects and fiber-optic blankets. Among them, a second lateral panel, also known as double phototherapy (DP), is frequently used.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Fototerapia simples versus dupla no tratamento de recém-nascidos a termo com hiperbilirrubinemia não-hemolítica

Silva¹,

Luco²,

Tapia³

et al. 2009

J. Pediatr. (Rio J.)

View full text Add to dashboard Cite

show abstract

“…Garg 16 and Tan 17 have devised systems that provide phototherapy both above and below the infant and a similar system has been commercially produced in the United States. * The availability of fiberoptic pads has made it easy to increase the surface area of the infant exposed to phototherapy and in preterm infants this type of ''double phototherapy'' is approximately twice as effective as single phototherapy.…”

Section: Surface Areamentioning

confidence: 99%

Phototherapy — Traditional and Nontraditional

2001

J Perinatol

View full text Add to dashboard Cite

“…1,2 Its noninvasive nature, easy availability, low cost and occurrence of few side effects have initially almost led to the assumption that it is innocuous. 3 The possibility that this may not be the case has been raised in several recent publications, which have shown that phototherapy is a photodynamic stress and can induce lipid peroxidation.…”

Section: Introductionmentioning

confidence: 99%

Estado oxidante/antioxidante total em recém-nascidos ictéricos antes e depois da fototerapia

Ayçicek¹,

Erel²

2007

J. Pediatr. (Rio J.)

View full text Add to dashboard Cite

Objective: To assess the effect of phototherapy on serum oxidant and antioxidant status in hyperbilirubinemic full-term newborns.Method: Thirty-four full-term infants from 3 to 10 days of age exposed to phototherapy were studied. The serum antioxidant status was assessed by measuring the total antioxidant capacity (TAC) and individual antioxidant components: vitamin C, uric acid, albumin, thiol contents and total bilirubin. The oxidant status was assessed by determining the total oxidant status (TOS), oxidative stress index (OSI) and individual oxidant components: malondialdehyde (MDA), and lipid hydroperoxide levels.Results: Vitamin C, uric acid, total bilirubin and MDA concentration were significantly lower, whereas serum TOS, lipid hydroperoxide and OSI levels were significantly higher after phototherapy (p < 0.05). There were significant positive correlations between serum total bilirubin and MDA (r = 0.434, p = 0.001). Conclusions:Although the MDA level was reduced after phototherapy, phototherapy has a negative impact on numerous parts of the oxidant/antioxidant defense system in jaundiced full-term newborns, exposing them to potential oxidative stress.J Pediatr (Rio J). 2007;83(4):319-322: Antioxidants, infant, malondialdehyde, oxidative stress, phototherapy.

show abstract

Phototherapy for Neonatal Jaundice

Cited by 64 publications

References 39 publications

Fototerapia simples versus dupla no tratamento de recém-nascidos a termo com hiperbilirrubinemia não-hemolítica

Fototerapia simples versus dupla no tratamento de recém-nascidos a termo com hiperbilirrubinemia não-hemolítica

Phototherapy — Traditional and Nontraditional

Estado oxidante/antioxidante total em recém-nascidos ictéricos antes e depois da fototerapia

Contact Info

Product

Resources

About