Photothermal and adsorption effects of silver selenide nanoparticles modified by different surfactants in nursing care of cancer patients

Abstract

Silver selenide nanoparticles have advantages of low cytotoxicity, desirable near-infrared light response characteristics, and easy surface modification, which attract increasing attention in chemo-photothermal therapy and nursing care of cancer patients. In this contribution, we synthesized Ag 2 Se nanoparticles modified by the surfactant of cetyltrimethylammonium bromide (CTAB) using a ligand exchange strategy. Their microstructure and composition were characterized by transmission electron microscopy, X-ray diffraction, X-ray Photo-electronic Spectroscopy, and Fourier transform infrared spectroscopy. The CTAB modified Ag 2 Se nanoparticles exhibited a uniform diameter distribution centered at ~12 nm. In order to investigate the photothermal and adsorption effects of CTAB-Ag 2 Se nanocomposites, we also prepared sodium dodecyl benzene sulfonate (SDBS) modified Ag 2 Se nanoparticles to make a comparison. The CTAB-Ag 2 Se nanoparticles showed high photothermal properties, a photothermal conversion efficiency of 20.1% and a high drug adsorption performance of 48.2 μg/mg. Importantly, the CTAB-Ag 2 Se-DOX presented an MCF-7 cell activity of only 27.3% under near-infrared radiation. The results revealed that the surface-modified Ag 2 Se nanoparticles with CTAB had stronger antitumor ability.

Crystal Structure of Colloidally Prepared Metastable Ag2Se Nanocrystals

“…In the case of Ag 2 Se, substantial changes in physical properties accompany solid–solid phase transitions . For example, the orthorhombic phase of Ag 2 Se is known to be a narrow-band-gap semiconductor in the bulk ( E g = 0.15 eV) and orthorhombic Ag 2 Se nanocrystals are promising for near-infrared detection and imaging applications and as topological insulators. − In contrast, the high-temperature cubic phase is electrically and ionically conductive, with highly mobile Ag + cations that move through a rigid-body-centered Se 2– sublattice. ,, These properties of cubic Ag 2 Se are desirable for solid-state electrolytes, ,, and the differences in electrical and thermal conductivity between orthorhombic and cubic Ag 2 Se have been used to optimize thermoelectric responses at temperatures near the boundary of the orthorhombic to cubic phase transition . Significantly less is known about the “tetragonal” phase of Ag 2 Se nanocrystals, in part because the crystal structure remains unresolved.…”

Ofloxacin-loaded Selenium-tellurium Nanoheterojunctions for Skin Infection and Wound Healing

“…Specific calculation of the photothermal conversion efficiency (η ) could be found in the supporting information. Theη was considered to 81.4%, which was superior to many previously reported selenium-based nanomaterial photothermal agents, such as bismuth selenide (Bi 2 Se 3 ) nanosheets (20.12%) [37], silver selenide (Ag 2 Se) nanoparticles (20.1%) [38], cuprous selenide (Cu 2 Se) nanosheets (61.16%) [39] and molybdenum selenide (MoSe 2 ) nanoflowers (61.8%) [40].…”

Nanomaterials and their composite scaffolds for photothermal therapy and tissue engineering applications

“…In addition to Au nanomaterials of various shapes, Ag nanomaterials have been used in PTT of tumors due to the LSPR properties and the toxicity of Ag + [77,78]. Similarly, Pt nanomaterials have also been reported to generate enough heat to ablate tumors under NIR laser irradiation [79,80].…”