Photothermal-responsive Prussian blue nanocages loaded with thrombin for tumor starvation therapy and photothermal therapy

Abstract

The goal of inhibiting tumor growth can be achieved by cutting off the supply of nutrients in the blood vessels of the tumor site, but how to effectively, accurately and...

MoS2 Nanocomposites Loaded with Zinc Phthalocyanine for NIR Light-Triggered Photothermal/Photodynamic Therapy of Breast Cancer

“…The temperature rise reached 34.8 °C for the FA-ZnPc-BSA/MoS 2 nanocomposite solution with a concentration of 200 μg/mL, and the photothermal conversion efficiency η T reaches 45.33% (Figure S6), and the infrared thermogram also clearly showed the temperature changes before and after laser irradiation (Figure c). Generally, after heating up, it can reach more than 40 °C to meet the requirements of photothermal treatment . Therefore, the experimental findings indicate that FA-ZnPc-BSA/MoS 2 nanocomposites have good power of photothermal conversion and its concentration of 12.5 μg/mL can meet the temperature requirements of PTT.…”

“…Generally, after heating up, it can reach more than 40 °C to meet the requirements of photothermal treatment. 38 Therefore, the experimental findings indicate that FA-ZnPc-BSA/MoS 2 nanocomposites have good power of photothermal conversion and its concentration of 12.5 μg/mL can meet the temperature requirements of PTT. The FA-ZnPc-BSA/MoS 2 nanocomposite solution can be steadily warmed up to the same temperature after multiple times of laser irradiation, and the effect of temperature rise and drop is very stable, not affected by the multiple irradiation (Figure 2b).…”

ROS-responsive polyprodrug micelles carrying suicide genes in combination with chemotherapy and gene therapy for prostate cancer treatment

“…At present, a wide variety of nanocarriers have been reported, such as polymer nanoparticles, liposomes, and nonmetals/metal nanoparticles. [12][13][14] Some carriers can also be endowed with imaging or other functions to achieve integrated diagnosis and treatment. [15][16][17] Many chemotherapeutic drug molecules have active groups, such as amino and hydroxyl groups, which can be linked by condensation polymerization to obtain polymer prodrugs.…”